Medical lubricant for sterilizing and balancing potential of hydrogen and preparation process of medical lubricant

A lubricant, pH technology, applied in the field of pharmaceutical excipients and its preparation method, can solve the problems of difficult cleaning, easy to contaminate clothes, unsatisfactory effect, etc., achieve cool touch, excellent mucosal compatibility, and assist in the recovery of wound tissue

Inactive Publication Date: 2013-04-03
JIANGSU PROVINCE JIANERKANG MEDICAL DRESSING CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the limitation of ingredients, the effect is not ideal, it is easy to stain clothes, and it is not easy to be absorbed by the body; later people also tried to use petroleum-based mineral oily substances such as petroleum jelly, baby oil, bath liquid, massage oil as lubrication; these substances are often viscous Too large, not easy to clean, easy to cause residue after use

Method used

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  • Medical lubricant for sterilizing and balancing potential of hydrogen and preparation process of medical lubricant

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Prepare Lubricant Solution

[0028] Mix 60 kg of glycerol, 10 kg of carbomer, 15 kg of polyethylene glycol, 2L of 0.4M acetate buffer and 4L of 0.3M borate buffer, stir for 1-2 hours, let stand overnight, centrifuge for 15min, remove Bubbles, and finally add pure water to 100L. Measure pH and viscosity.

[0029] Results: The pH is 6.7, the viscosity at 20C is 20-35Pa·s, and the viscosity at 32°C is 86-110Pa·s.

Embodiment 2

[0031] Prepare Lubricant Solution

[0032] Stir 50kg of glycerin, 15kg of carbomer, 20kg of polyethylene glycol and 2L of 0.4M acetate buffer for 1-2 hours, let stand overnight, centrifuge for 15min to remove air bubbles, and finally add pure water to 100L. Measure pH and viscosity.

[0033] Results: The pH is 5.7, the viscosity at 20°C is 23-33Pa·s, and the viscosity at 32°C is 90-105Pa·s.

[0034] The preparation method of the medical lubricant of sterilized balance pH, is characterized in that, described method comprises the steps: 30-75wt% glycerin, 5-15wt% carbomer (Carbomer), 10-20wt% polyethylene glycol, 10 -20wt% acid-base buffer mixed, swollen and dissolved to form the medical lubricant for sterilization and balanced pH

[0035] Such as figure 1 A schematic process flow diagram of the present invention is shown. After the preparation of the solution is completed, the detection is carried out. The qualified lubricants will be packaged by the machine. When operati...

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PUM

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Abstract

The invention provides a medial lubricant for sterilizing and balancing potential of hydrogen. The lubricant comprises the following components based on the gross weight: 30 to 75wt% of glycerol, 5 to 15wt% of Carbomer, 10 to 20wt% of polyethylene glycol, and 10 to 20wt% of acid-base buffer agent, wherein the acid-base buffer agent is selected from acetic acid buffer pair, boric acid buffer pair, carbonic acid buffer pair, phosphoric acid buffer pair, citric acid buffer pair, acetate buffer pair, borate buffer pair, carbonate buffer pair, phosphate buffer pair and citrate buffer pair.

Description

technical field [0001] The invention relates to the field of health and sanitation, in particular to a pharmaceutical auxiliary material and a preparation method thereof. Background technique [0002] People have tried to apply lubricants to the human body for a long time, but the large-scale application is still after 1950. Lubricants (liquids) were first used in clinical medical examinations of the human body: many medical devices will cause mechanical damage to varying degrees when they penetrate into the human body, and lubricants can minimize damage to body tissues and mucous membranes. Early people used vegetable oils such as olive oil. However, due to the limitation of ingredients, the effect is not ideal, it is easy to stain clothes, and it is not easy to be absorbed by the body; later people also tried to use petroleum-based mineral oily substances such as petroleum jelly, baby oil, bath liquid, massage oil as lubrication; these substances are often viscous If it ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K49/00
Inventor 陈国平陈罗俊戚建勇
Owner JIANGSU PROVINCE JIANERKANG MEDICAL DRESSING CO LTD
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