Preparation process for astragalus superfine powder particle decoction pieces

A granule decoction piece and preparation technology, which is applied in the field of preparation technology of Astragalus ultrafine powder granule decoction piece, can solve problems affecting clinical efficacy and drug safety, non-standard processing, inconsistent tablet specifications, etc., and achieve saving medicinal material resources and pharmaceutical excipients resources, increase the dissolution rate and dissolution amount, and shorten the effect of suffering time

Active Publication Date: 2013-05-01
四川国强中药饮片有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] There are obvious regional differences in the traditional usage habits of Chinese herbal pieces. The processing methods of the pieces are different in different regions. The dissolution rate is low and the utilization rate of medicinal materials is low, which seriously affects the curative effect of traditional Chinese medicine
[0004] The existing mode of use of decoction pieces mostly adopts the method of pre-prescription weighing and blending. Large-package decoction pieces are usually sold after unpacking. The identity of the medicine is poor, and there is uncertainty in the effective drug dosage. The types of decoction pieces currently used are limited to: slices, segments , block, powder, cake, glue, and extraction formula granules, there are the same species but their quality varies greatly, and the clinical efficacy is very different. The quality of medicinal materials and their decoction pieces is difficult to achieve uniformity; The clinical curative effect and drug safety are important; there are very few Chinese medicinal materials suitable for processing into gelatinized Chinese medicine decoction pieces, and they cannot be widely used; extraction formula granules, also known as Chinese medicine granule decoction pieces, decoction-free pieces, single-flavor Chinese medicine concentrated granules, are convenient, Fast, safe, hygienic, convenient for mechanized production, unified quality standards, easy to take, carry, and deploy; The torment process in the process of citing traditional Chinese medicine is eliminated, so that it loses the synergistic effect of co-decoction of various traditional Chinese medicines, and its efficacy is far inferior to that of traditional Chinese medicine decoction.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] The preparation technology of Radix Astragali superfine powder particle decoction piece, it comprises the following steps:

[0026] S1. Purification: remove impurities from the raw materials of Astragalus membranaceus that have passed the test, and wash them;

[0027] S2. Slicing: Slicing the washed Astragalus Chinese herbal medicine, the thickness of the slice is 0.3-0.5cm;

[0028] S3, drying: put the flaky Astragalus membranaceus obtained in step S2 into a drier for drying treatment, and dry until the water content is 3%;

[0029] S4. Low-temperature ultrafine pulverization: add the dried flaky Astragalus membranaceus into a superfine pulverizer, keep the temperature at -20°C, and pulverize until the particle size is 1000 mesh;

[0030] S5, mixing: the astragalus powder obtained in step S4 is mixed evenly, and the color and luster are consistent;

[0031] S6. Granulation: Add drinking water accounting for 30% of its weight to the uniformly mixed astragalus powder, ...

Embodiment 2

[0037] The preparation technology of Radix Astragali superfine powder particle decoction piece, it comprises the following steps:

[0038] S1. Purification: remove impurities from the raw materials of Astragalus membranaceus that have passed the test, and wash them;

[0039] S2. Slicing: Slicing the washed Astragalus Chinese herbal medicine, the thickness of the slice is 0.3-0.5cm;

[0040] S3, drying: put the flaky Astragalus membranaceus obtained in step S2 into a drier for drying treatment, and dry until the water content is 8%;

[0041] S4. Low-temperature ultrafine pulverization: add the dried flaky Astragalus membranaceus into a superfine pulverizer, keep the temperature at -50°C, and pulverize until the particle size is 100 mesh;

[0042] S5, mixing: the astragalus powder obtained in step S4 is mixed evenly, and the color and luster are consistent;

[0043] S6. Granulation: add 25% drinking water to the uniformly mixed astragalus powder, and stir evenly to make a soft...

Embodiment 3

[0049] The preparation technology of Radix Astragali superfine powder particle decoction piece, it comprises the following steps:

[0050] S1. Purification: remove impurities from the raw materials of Astragalus membranaceus that have passed the test, and wash them;

[0051] S2. Slicing: Slicing the washed Astragalus Chinese herbal medicine, the thickness of the slice is 0.3-0.5cm;

[0052] S3, drying: put the flaky Astragalus membranaceus obtained in step S2 into a drier for drying treatment, and dry until the water content is 5%;

[0053] S4. Low-temperature superfine pulverization: add the dried flaky Astragalus membranaceus into a superfine pulverizer, keep the temperature at -30°C, and pulverize until the particle size is 500 mesh;

[0054] S5, mixing: the astragalus powder obtained in step S4 is mixed evenly, and the color and luster are consistent;

[0055] S6. Granulation: Add drinking water accounting for 60% of its weight to the uniformly mixed astragalus powder, a...

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Abstract

The invention discloses a preparation process for astragalus superfine powder particle decoction pieces, comprising the following steps that S1, cleansing: Chinese herbal medicine raw material, namely astragalus, is subjected to impurity removal and is cleanly washed; S2, the astragalus is cut into slices; S3, the astragalus is dried until the water content is 3-8 percent; S4, low-temperature superfine grinding is carried out at the temperature of minus 50 DEG C to minus 20 DEG C until the granularity is 100-1000 meshes; S5, mixing is carried out; S6, palletizing is carried out, and the granularity of prepared particles is 12-24 meshes; S7, blending is carried out; and S8, weighing and packaging are carried out. The preparation process for the astragalus superfine powder particle decoction pieces has the beneficial effects that no excipients are added, all natural features of the Chinese herbal medicine are effectively remained, the dissolving-out speed and dissolving-out quantity of active ingredients are improved, the advantage of common decoction and taking of traditional Chinese medicament is maintained, the synergistic effect of various formulas of Chinese herbal medicine decoction pieces is played, the curative effect is improved, the identity of product quality and active ingredient content of particles is strong, and the implementation of mechanical, large-scale and batch production is facilitated.

Description

technical field [0001] The invention relates to the technical field of processing and processing of traditional Chinese medicinal materials, in particular to a preparation process of astragalus superfine powder granule decoction pieces. Background technique [0002] Traditional Chinese medicine is the precious wealth of the Chinese nation, has a history of thousands of years of development, and plays an indispensable role in the prevention and treatment of diseases. High-efficiency and high-quality traditional Chinese medicine products are the fundamental guarantee for the safety and effectiveness of clinical medication. Chinese medicine decoction pieces are one of the important means of traditional Chinese medicine medicine, but with the improvement of people's drug use level, there are many shortcomings in the use of traditional Chinese medicine decoction pieces in the process of making soup, mainly in: [0003] There are obvious regional differences in the traditional us...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/481A61K9/16
Inventor 葛强
Owner 四川国强中药饮片有限公司
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