Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation method and applications of deoxymononucleotide natrium-containing drug composition and preparation thereof

A technology of deoxymononucleotide sodium and deoxyriboseguanine nucleotide sodium, which is applied in the field of medicine, can solve the problems of no reports, etc., and achieve obvious and excellent clinical effects

Inactive Publication Date: 2013-05-15
BEIJING SAISHENG PHARMA
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report for the pharmaceutical composition containing sodium deoxyribonucleotides (the relationship between the composition ratio of sodium deoxyribonucleotides and pharmacodynamics) for the excellent effect

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Precisely weigh 15.7 g (grams) of sterile, pyrogen-free deoxyribose adenine nucleotide sodium, 11.8 g deoxyribose thymidine nucleotide sodium, 13.1 g deoxyribose guanine nucleotide sodium, and deoxyribose cytosine core Put 13.1g of sodium glycoside in a clean liquid preparation container, add water for injection to 2.15 liters, mix well, sterilize and filter, fill 2.15ml / cartridge, seal, and check for leaks under the condition of a vacuum of -80Kpa (kiloPascals) , the quality inspection is qualified as a finished product (can be considered as a pharmaceutical composition containing sodium deoxynucleotide).

Embodiment 2

[0048] Accurately weigh 13.4g of deoxyribose adenine nucleotide sodium, 13.4g of deoxyribose thymidine nucleotide sodium, 13.4g of deoxyribose guanine nucleotide sodium, and 13.4g of deoxyribocytosine nucleotide sodium, add water for injection to 2.15 liters, fully mixed, sterilized and filtered, filled with 2.15ml / bottle, sealed, leak tested at a vacuum of -80Kpa, and the quality inspection is a finished product.

Embodiment 3

[0050] Accurately weigh 20.2g of deoxyribose adenine nucleotide sodium, 20.2g of deoxyribose thymidine nucleotide sodium, 6.7g of deoxyribose guanine nucleotide sodium, and 6.7g of deoxyribocytosine nucleotide sodium, add water for injection to 2.15 liters, fully mixed, sterilized and filtered, filled with 2.15ml / bottle, sealed, leak tested at a vacuum of -80Kpa, and the quality inspection is a finished product.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a deoxymononucleotide natrium-containing drug composition and applications thereof, and belongs to the technical field of medicine. The deoxymononucleotide natrium-containing drug composition contains deoxyribose adenine nucleotide natrium, deoxyribose thymine nucleotide natrium, deoxyribose guanine nucleotide natrium, and deoxyribose cytosine nucleotide natrium, wherein a weight ratio of the deoxyribose adenine nucleotide natrium to the deoxyribose thymine nucleotide natrium to the deoxyribose guanine nucleotide natrium to the deoxyribose cytosine nucleotide natrium is (3-10):(2-13):(2-11):(1-10). The deoxymononucleotide natrium-containing drug composition has excellent effects in clinic, particularly in adjunctive treatments of acute hepatitis and chronic hepatitis.

Description

technical field [0001] The invention relates to a preparation method and application of a pharmaceutical composition containing sodium deoxymononucleotide in different proportions and its preparation, belonging to the technical field of medicine. Background technique [0002] Viral hepatitis, especially hepatitis B virus infection (HBV), is still a serious public health problem worldwide. According to the report of the World Health Organization, about 2 billion people in the world have been infected with HBV, of which 350 million people are chronic HBV infected people, and about 1 million people die every year from liver failure, liver cirrhosis and primary hepatocellular carcinoma caused by HBV infection (PHC). my country is one of the high-incidence areas of viral hepatitis. According to the 2006 national hepatitis B epidemiological survey, there are about 93 million chronic HBV infected people in my country, of which about 20 million are chronic hepatitis B patients. Al...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/708A61K31/7076A61K31/7072A61K31/7068A61P3/00A61P1/16A61P7/06A61P31/20
Inventor 栾美丽马骉姜桂荣孔双泉
Owner BEIJING SAISHENG PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com