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Fat oxidation or energy metabolism enhancer

A combustion accelerator, energy metabolism technology, applied in metabolic diseases, the function of food ingredients, medical raw materials derived from angiosperms, etc., can solve the problem of no antihypertensive effect and other problems

Active Publication Date: 2013-05-15
KAO CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, even though chlorogenic acid has an antihypertensive effect, it sometimes does not show sufficient antihypertensive effect in coffee drinks containing a large amount of hydroxyhydroquinone (Non-Patent Document 3)

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0068] Examples are shown below to further describe the present invention in detail.

reference example 1

[0069] Reference Example 1 Preparation of Roasted Coffee Bean Extract

[0070] Into the column extractor equipped with a metal sieve, put the coffee obtained by mixing two kinds of Brazil beans ground into medium grains with roasting degrees L14 and L16.5 measured by the color difference meter according to the mixing ratio (1:1) 60 kg of beans were poured into ion-exchanged water at 98° C. to obtain 413 kg of roasted coffee bean extract. The obtained extract was appropriately fractionated to adjust the concentration. A roasted coffee bean extract (corresponding to a placebo drink to be described later) having the following analysis values ​​before activated carbon treatment was prepared.

[0071] Hydroxyhydroquinone (HHQ) concentration: 36.5mg / kg

[0072] Chlorogenic acid concentration: 1805mg / kg

[0073] Caffeine concentration: 385.9mg / kg

[0074] Next, the extract was passed through a column filled with activated carbon Baijiu WH2C42 / 80L SS (Japan EnviroChemicals.ltd) (t...

Embodiment 1

[0116] Example 1 Effect of ingestion of roasted coffee bean extract from which HHQ has been removed, on postprandial energy metabolism.

[0117] (Materials and methods)

[0118] A placebo drink and a test drink were used as the tested drinks. Beverages are all sterilized under high temperature and high pressure according to the prescribed method to make 185g canned coffee beverage. As a placebo drink, the activated carbon-treated roasted coffee bean extract described in Reference Example 1 was used, and the HHQ content in the drink was 6.75 mg / 185 g. On the other hand, the activated carbon-treated roasted coffee bean extract described in Reference Example 1 was used as a test drink, and the HHQ content in the drink was 0.27 mg / 185 g.

[0119] In addition, the placebo drink and the test drink contained the same levels of chlorogenic acids (334 / 185g and 312mg / 185g, respectively) and caffeine (71.4 / 185g and 66.0mg / 185g, respectively) as the usual coffee drinks .

[0120] The ...

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Abstract

Provided are a composition, a medicinal agent, a quasi drug, a food, a beverage, a pet food, a feed and the like, which are highly safe and have an excellent fat-oxidation- or energy-metabolism-enhancing activity. Specifically provided are: a roasted coffee bean extract which can be used for enhancing fat oxidation or energy metabolism, contains a chlorogenic acid compound or a salt thereof, and has a hydroxyhydroquinone content of less than 0.1 mass% relative to the content of the chlorogenic acid compound; and use of a roasted coffee bean extract containing a chlorogenic acid compound or a salt thereof and having a hydroxyhydroquinone content of less than 0.1 mass% relative to the content of the chlorogenic acid compound for the production of a fat oxidation or energy metabolism enhancer.

Description

technical field [0001] The present invention relates to promoters of lipid burning or energy metabolism. Background technique [0002] Obesity refers to a state in which intake energy such as carbohydrates or lipids is excessively accumulated as fat under the skin or around internal organs, and is higher than normal body weight. In addition, in recent years, the concept of metabolic syndrome has attracted attention. Metabolic syndrome refers to the excessive accumulation of visceral fat (obesity), combined with abnormal glucose tolerance (hyperglycemia), high neutral fat (hyperlipidemia), and high blood pressure. Arteriosclerosis-prone state, a state in which the risk of suffering from lifestyle-related diseases is increased. [0003] In Japan, according to the diagnostic criteria for metabolic syndrome published in 2005, if the waist is more than 85cm for men, and more than 90cm for women, and people who meet more than 2 of the following 3 items are metabolic syndrome: (1)...

Claims

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Application Information

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IPC IPC(8): A61K36/18A61K31/05A61K31/216A61K36/00A61P3/04A61P3/06A23L1/30
CPCA61K31/216A23V2002/00A61K36/00A61K36/74A61K31/05A23F5/185A23F5/24A23L1/3002A23L33/105A61P3/04A61P3/06A23V2200/332A23V2250/2108A61K2300/00
Inventor 曾我聪子太田宣康下丰留玲村瀬孝利
Owner KAO CORP
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