Compound probiotic, application thereof for treating anaphylactic diseases and allergy free probiotic electuary for pregnant and lying-in women
What is Al technical title?
Al technical title is built by PatSnap Al team. It summarizes the technical point description of the patent document.
A technology of compound probiotics and allergy probiotics, applied in the field of medicine, can solve the problem of low efficacy in preventing and treating allergies
Active Publication Date: 2013-06-26
贝因美(杭州)食品研究院有限公司
View PDF4 Cites 15 Cited by
Summary
Abstract
Description
Claims
Application Information
AI Technical Summary
This helps you quickly interpret patents by identifying the three key elements:
Problems solved by technology
Method used
Benefits of technology
Problems solved by technology
[0007] However, the above-mentioned patents can only promote the secretion of γ-interferon (IFN-γ), and the effective rate of preventing and treating allergies is not high.
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more
Image
Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
Click on the blue label to locate the original text in one second.
Reading with bidirectional positioning of images and text.
Smart Image
Examples
Experimental program
Comparison scheme
Effect test
Embodiment 1
[0062] The preparation of embodiment 1 compound probiotics
[0063] Bifidobacterium lactis Bi-07 0.3mg
[0064] Lactobacillus rhamnosus LR22 0.3mg
[0065] Lactobacillus acidophilus NCFM 0.3mg
[0066] After mixing, the compound probiotics are obtained. Among them, the content of Bifidobacterium lactis Bi-07 is 9.0×10 7 CFU / g, the content of Lactobacillus rhamnosus LR22 is 9.0×10 7 CFU / g, Lactobacillus acidophilus NCFM content is 6.0×10 7 CFU / g.
Embodiment 2
[0067] The preparation of embodiment 2 compound probiotics
[0068] Bifidobacterium lactis Bi-07 2g
[0069] Lactobacillus rhamnosus LR22 4g
[0070] Lactobacillus acidophilus NCFM 3g
[0071] After mixing, the compound probiotics are obtained. Among them, the content of Bifidobacterium lactis Bi-07 is 6.0×10 11 CFU / g, the content of Lactobacillus rhamnosus LR22 is 1.2×10 12 CFU / g, Lactobacillus acidophilus NCFM content is 6.0×10 11 CFU / g.
Embodiment 3
[0072] The preparation of embodiment 3 compound probiotics
[0073] Bifidobacterium lactis Bi-07 3g
[0074] Lactobacillus rhamnosus LR22 2g
[0075] Lactobacillus acidophilus NCFM 4g
[0076] After mixing, the compound probiotics are obtained. Among them, the content of Bifidobacterium lactis Bi-07 is 9.0×10 11 CFU / g, the content of Lactobacillus rhamnosus LR22 is 6.0×10 11 CFU / g, Lactobacillus acidophilus NCFM content is 8.0×10 11 CFU / g.
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
PUM
Login to view more
Abstract
The invention relates to the field of medicines, and in particular to compound probiotic, application thereof for treating anaphylactic diseases and allergy free probiotic electuary for pregnant and lying-in women. The compound probiotic consists of bifidobacterium Bi-07, lactobacillus rhamnosus LR22, lactobacillus acidophilus NCFM. The compound probiotic not only can irritate secretion of IFN-gamma and IL-2 in animal body, but also inhibit secretion of immune globulin E (IgE) and IL-4 so as to prevent and treat anaphylactic diseases. The invention further provides a medical preparation comprising the compound probiotic and allergy free probiotic electuary for pregnant and lying-in women. The pharmacodynamic test shows that the medical preparation has remarkable effect of improving IL-2 and IFN-gamma. In addition, compared with the control group, the content of IgE in the test group is further remarkably reduced. Long-term clinical tests show that the medical preparation comprising the compound probiotic provided by the invention is free from untoward effects to human body.
Description
technical field [0001] The invention relates to the field of medicine, in particular to compound probiotics, their application in the treatment of allergic diseases and anti-allergic probiotic granules for pregnant and lying-in women. Background technique [0002] Allergy refers to an acquired potential to produce a harmful immune response to a normally harmless substance, and is an allergic disease. Clinically common pruritus, asthma, allergic rhinitis, allergic dermatitis such as eczema, urticaria and so on. It is generally believed that allergic reactions include early specific immune responses and late inflammatory responses. Allergens (eg, milk, pollen, mite dust) have been reported to form early allergic responses by stimulating high-affinity immunoglobulin (IgE) receptors. When IgE enters the blood, it comes into contact with the surface membranes of mast cells and basophils in the body's epithelial mucous membranes, such as the respiratory tract, gastrointestinal t...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
Application Information
Patent Timeline
Application Date:The date an application was filed.
Publication Date:The date a patent or application was officially published.
First Publication Date:The earliest publication date of a patent with the same application number.
Issue Date:Publication date of the patent grant document.
PCT Entry Date:The Entry date of PCT National Phase.
Estimated Expiry Date:The statutory expiry date of a patent right according to the Patent Law, and it is the longest term of protection that the patent right can achieve without the termination of the patent right due to other reasons(Term extension factor has been taken into account ).
Invalid Date:Actual expiry date is based on effective date or publication date of legal transaction data of invalid patent.