Polypeptide used for preparing O type peptide vaccine of cattle foot-and-mouth disease and preparation methods and applications thereof

A bovine foot-and-mouth disease and peptide vaccine technology, which is applied in the field of medicine, can solve the problems of not being able to effectively protect animals, affecting the use of new vaccines, and being ineffective, and achieve the effects of good immune efficacy, good application prospects, and no biological safety.
CN103183728BActive Publication Date: 2015-06-10中国牧工商集团有限公司 +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
中国牧工商集团有限公司
Publication Date
2015-06-10

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Abstract

The invention provides polypeptide used for preparing O type peptide vaccine of cattle foot-and-mouth disease. The polypeptide comprises an amino acid sequence presented by SEQ ID NO.1 and the peptide vaccine containing the polypeptide. The O type synthetic peptide vaccine of cattle foot-and-mouth disease provided by the invention has excellent immune efficacy, and cannot cause the problems of fever, swelling and the like existing in traditional vaccines, so that the vaccine can effectively respond to antigenic variation of current foot-and-mouth disease virus, prevents biosecurity problems, is easy to synthesize in a large scale, and has an excellent application prospect. The invention further provides preparation methods and pharmaceutical applications of the polypeptide and the peptide vaccine.
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Description

technical field

[0001] The invention belongs to the technical field of medicine, in particular, the invention relates to a polypeptide used for preparing a bovine foot-and-mouth disease O-type peptide vaccine, a vaccine containing the polypeptide and a preparation method thereof. Background technique

[0002] Foot and mouth disease (FMD) is an acute, highly contagious, febrile infectious disease of cloven-hoofed animals, which is widely distributed in the world. Foot-and-mouth disease is highly contagious and spreads rapidly. After infecting pigs, cattle, sheep and other livestock, it will lead to the death of young animals and a sharp decline in the production capacity of adult animals. Therefore, it seriously endangers the development of animal husbandry and the production and supply of meat and animal products. At present, foot-and-mouth disease has greatly blocked and restricted the market circulation and international trade of animals and animal products, causing huge e...

Claims

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