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Oral medical composition for preventing and/or treating cold and application thereof

A composition and drug technology, which is applied in the direction of drug combination, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve problems such as heavy taste, aggravated disease, oral mucosa easy to cause other bacterial infections, etc.

Inactive Publication Date: 2013-07-24
陆媛
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] A variety of Western medicines and some traditional Chinese medicine ingredients commonly used to treat cold medicines have good effects or bad taste. They are usually bitter, have a strange or strong taste, and are not easily accepted by users. They can only be swallowed and are difficult for people to swallow. Accept oral administration, or it is very irritating, and oral administration is easy to burn the oral mucosa, which will increase pain and aggravate the condition. Burning the oral mucosa can easily lead to other bacterial infections. Drugs are likely to cause certain damage to the gastric mucosa

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0076] Each tablet of the representative compound preparation of the present invention contains: diclofenac sodium (diclofenac) 15mg, artificial bezoar 15mg, chlorpheniramine maleate (chlorpheniramine) 2.5mg; auxiliary components are watermelon frost, borneol, peppermint oil, Menthol, the dosage of these auxiliary components is 1 / 5 to 1 / 3 of the traditional drug concentration, which can be increased or decreased, and has no significant impact on the therapeutic effect of the medicine of the present invention; the auxiliary materials are added with dextrin, sucrose (or xylitol) , citric acid, magnesium stearate, talcum powder, food coloring, food flavor. The amount of excipients is 3-10 times that of traditional swallowed medicines (compared with the amount of excipients in a traditional swallowed medicine with the same active ingredient for the treatment of colds), in order to reduce the relative "concentration" of medicines that are not suitable for direct oral administration ...

Embodiment 2

[0083] The commercially available antibacterial drug (compound sulfonamide drug) used to treat colds with a buccal taste that is not easily accepted by patients is added with pharmaceutically acceptable excipients, mixed well, and made into a buccal tablet for 13 minutes. The concentration of the active ingredient in the buccal tablet is 1 / 5 of that of the original compound sulfa medicament.

[0084] The buccal tablet of this embodiment was used by 50 people who had early symptoms of colds, and none of the oral mucosa was burned, and the mouthfeel was acceptable. The time for taking it was about 12-14 minutes. Mild bacterial infection of the throat and trachea was relieved, purulent sputum disappeared, and a piece of medicine cured the mild infection complicated by early cold. In the treatment of the above 50 patients with early cold symptoms using the product of the present invention, not all of them were early cold symptoms caused by common cold virus infection, but early sy...

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Abstract

The invention provides an oral medical composition for preventing and / or treating cold and application thereof. The oral medical composition comprises effective components for preventing and / or treating cold or early cold complication trend, and medically acceptable auxiliary materials, or further comprises assistant components, wherein the effective components for preventing and / or treating cold or early cold complication trend comprise medical components which are not suitable for being orally taken directly, such as components which are greatly irritating to mouth mucosa or bitter, or smelly; and the proportion of the medically acceptable auxiliary materials in the oral medical composition is greater than that of the auxiliary materials in the conventional oral medical composition for preventing and / or treating cold. By means of the technology provided by the invention, medicines which are not accepted and are not directly used or inhibited from oral administration are prepared to efficient medical preparations which can be safely taken and welcomed by patients, and have the remarkable effect of preventing and / or treating cold in early stage.

Description

technical field [0001] The present invention relates to a buccal pharmaceutical composition for preventing and / or treating colds and its application, in particular to a highly effective buccal pharmaceutical composition containing medicines for preventing and treating colds which are traditionally considered unsuitable for buccal administration. Technology of oral preparations, prepared buccal pharmaceutical preparations and related applications. Background technique [0002] Flu is a common, frequently-occurring, contagious, and epidemic disease, but if it is not treated early, it will easily cause serious complications, even life-threatening. Most patients don’t pay enough attention to early onset symptoms or early signs of cold complications, and wait until the condition is severe before going to the doctor, taking medicine, taking medicine or even being hospitalized. A common cold usually costs several hundred yuan to two thousand yuan to treat, and hospitalization costs...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K45/00A61K45/06A61K47/36A61K47/26A61K47/12A61K47/04A61K9/20A61P11/00
Inventor 陆媛
Owner 陆媛
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