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Skin external preparation composition of Moringa oleifera seed extract

A technology for skin external preparations and Moringa seeds, which can be used in drug combinations, skin care preparations, skin diseases, etc. It can solve the problems of limited use, insufficient whitening effect, skin safety, dosage form stability, etc., and achieve high whitening effect Effect

Active Publication Date: 2018-06-01
AMOREPACIFIC CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In order to treat or alleviate the symptoms of abnormal skin pigmentation and excessive melanin pigmentation caused by exposure to ultraviolet rays, ascorbic acid, kojic acid, arbutin, hydroquinone, glutathione, and their derivatives have been used in the past. Substances with tyrosinase activity, etc. are mixed in cosmetics or pharmaceuticals, but their usability is limited due to problems such as insufficient whitening effect, safety to skin, and stability of dosage forms when mixed in cosmetics.

Method used

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  • Skin external preparation composition of Moringa oleifera seed extract
  • Skin external preparation composition of Moringa oleifera seed extract
  • Skin external preparation composition of Moringa oleifera seed extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] The preparation of embodiment 1 common germinated Moringa oleifera seed extract

[0028] Moringa oleifera seeds in a germinated state are put into a solvent of 70% by weight of purified water and 30% by weight of ethanol, and placed at 25° C. for 6 hours to extract active ingredients. After extraction, filter once in a filter with 3 μm pores, once in a filter with 1 μm pores to eliminate foreign matter, and finally use a sterilizing filter to eliminate microorganisms to obtain common Moringa oleifera seed extract.

Embodiment 2

[0029] The preparation of embodiment 2 subcritical Moringa oleifera seed extract

[0030] The Moringa oleifera seeds in the non-germinated state are extracted with a subcritical extraction device under a high pressure of 100 MPa to extract active ingredients. After extraction, filter once in a filter with 1.2 μm pores, once in a filter with 0.45 μm pores, once in a filter with 0.2 μm pores, eliminate foreign matter and microorganisms, and obtain subcritical Moringa oleifera seeds Extract.

Embodiment 3

[0031] The preparation of embodiment 3 subcritical germinated Moringa oleifera seed extract

[0032] The Moringa oleifera seeds in the germinated state are extracted with a subcritical extraction device under a high pressure of 100 MPa to extract active ingredients. After extraction, filter once in a filter with 1.2 μm pores, once in a filter with 0.45 μm pores, once in a filter with 0.2 μm pores, eliminate foreign matter and microorganisms, and obtain subcritical Moringa oleifera seeds Extract.

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Abstract

The invention relates to skin external composition containing drumstick tree seed extract, particularly relates to extract prepared by germinated drumstick tree seeds, or extract prepared by tree seeds using a subcritical extraction method. Compared with the previous common drumstick seed extract, the invention provides drumstick seed extracts containing many kinds and a large amount of effective constituents, and these extracts are used for performing higher efficiency.

Description

technical field [0001] The present invention relates to an external skin preparation composition containing Moringa oleifera seed extract, specifically, an extract prepared from germinated Moringa oleifera seed, or a subcritical extract of Moringa oleifera seed extracts that contain many types and a large amount of active ingredients can be provided compared to Moringa oleifera seed extracts, and by using these extracts, higher efficacy can be exhibited. Background technique [0002] Human skin color is determined by various factors such as the activity of melanin-producing melanocytes, the distribution of blood vessels, the thickness of the skin, and the content of carotenoids, bilirubin, and other pigments inside and outside the human body. In particular, a pigment called melanin produced by melanocytes through the action of various enzymes such as tyrosinase is the most important factor. In the pigment formation of melanin, genetic factors, hormone secretion, related phy...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K36/48A61Q19/02A61Q19/08A61P17/00A61P17/18A61K131/00
CPCA61K8/9789A61K36/484A61K36/73A61Q19/02
Inventor 姜显瑞申甫贤蔡秉根韩相勋
Owner AMOREPACIFIC CORP