Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for preparing lactone through catalyzing oxidation of ketone compound

A ketone compound and a technology for the compound are applied in the field of catalyzing the oxidation of ketone compounds to prepare lactones, which can solve the problems of limited practical application and safety problems, and achieve the effects of simple process, easy separation and good industrial application prospects.

Active Publication Date: 2013-09-04
山东尚正新材料科技股份有限公司
View PDF6 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The patent (CN102408404A) reported a method of using oxygen as an oxidant to catalyze the oxidation of cyclohexanone to prepare caprolactone. This method uses an azo free radical initiator in the reaction process, which has safety problems and is limited in practical application.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] In 10 mL of ethyl acetate solution containing 5 mg of hydroxylated multi-walled carbon nanotubes, add 2 mmol of cyclohexanone and 2 mmol of benzaldehyde, feed oxygen, and stir the reaction at a temperature of 25 ° C for 4 hours. After detection and analysis, the cyclohexanone The conversion rate of hexanone was 85%, and the selectivity of ε-caprolactone was greater than 99%.

[0018]

Embodiment 2

[0020] In 10 mL of 1,2-dichloroethane solution containing 10 mg of carboxylated multi-walled carbon nanotubes, add 2 mmol of 4-methylcyclohexanone and 8 mmol of benzaldehyde, and stir the reaction at 120 °C for 5 hours , After detection and analysis, the conversion rate of 4-methylcyclohexanone is 97%, and the selectivity of 4-methylcyclohexanolactone is greater than 99%.

[0021]

Embodiment 3

[0023] In 10 mL of sec-butyl acetate solution containing 10 mg of carboxylated single-walled carbon nanotubes, 2 mmol of 2-adamantone and 6 mmol of benzaldehyde were added, and the reaction was stirred at 30°C for 8 hours. After detection and analysis, 2- The conversion rate of adamantone was 92%, and the selectivity of 2-adamantolactone was greater than 99%.

[0024]

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a method for preparing lactone through catalyzing the oxidation of a ketone compound. The method which treats the ketone compound as a raw material and carbon nanotubes as a catalyst comprises a step of adding an organic solvent and an assistant, and a step of carrying out a catalysis reaction at 25-120DEG C under normal pressure to obtain a lactone compound in a high selectivity manner. The method has the advantages of simple process, mild condition, high selectivity, safety, easy catalyst recovery and the like.

Description

technical field [0001] The invention relates to a method for preparing lactone, in particular to a method for preparing lactone by catalyzing the oxidation of ketone compounds. Background technique [0002] Lactone is an important intermediate in organic synthesis, such as ε-caprolactone, which is widely used in the synthesis of polycaprolactone (PCL) and blended modified resins for various purposes. At present, in the method for preparing lactones by Baeyer-Villiger oxidation reaction, the oxidants used are usually organic peracids such as peracetic acid, peroxybenzoic acid, etc., and the use of such oxidants is not only costly, but also exists in actual operation. Many potential safety hazards limit the practical application of this process. [0003] Therefore, the preparation of lactones by Baeyer-Villiger oxidation using environment-friendly and safe oxygen / air as an oxidant has attracted much attention. The patent (CN102408404A) reports a method for preparing caprolac...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C07B41/12C07D313/04C07D313/10C07D309/30C07C67/42C07C69/14C07C69/24C07C69/78
Inventor 纪红兵陈韶云周贤太陶旺聪
Owner 山东尚正新材料科技股份有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com