Manufacturing method of individualized stent for repairing defect of more than four tooth positions on one side of low jawbone

Abstract

The invention discloses a manufacturing method of an individual stent for repairing defect of more than four tooth positions on one side of a low jawbone. The manufacturing method includes designing a repairing model of personalized appearance and an internal microstructure of individual defect through a CT (computed tomography) scan and image combined method and a reverse engineering method, obtaining a to-be-repaired body of a defect area through a cutting algorithm and manufacturing the to-be-repaired body through an EBSM (electron beam selective melting) method after being designed by a BOOL algorithm; implanting a three-dimensional metal stent into the low jawbone defect area; adopting titanium bolts to fix the to-be-repaired body and broken ends of two fractured bones; adding osteogenesis materials and autologous bone marrow strmal cells to the broken ends of the two fractured bones; suturing soft tissues and implanting an implant after bone formation is performed; finally completing repairing of false teeth. By the manufacturing method, bone growth can be better promoted and guided, effect of bone combination of the implant and surrounding bones is good, and repairing is facilitated in the long run.

Description

technical field [0001] The invention relates to a manufacturing method of a tissue engineering bracket for mandibular defect repair. Background technique [0002] In recent years, maxillofacial defects, especially mandibular defects, caused by tumors, infections, traffic accidents, etc., have been increasing year by year. In Europe alone, 1.5 million people need craniofacial surgery for bone repair every year, of which a considerable number One part is surgery on the mandible. [0003] The current mandibular defect repair surgery mainly adopts autologous bone grafting and metal plate prosthetic implantation. Vascularization surgery is very difficult, resulting in insufficient blood supply to the implant, which makes it difficult to control the absorption of the autologous bone implant and affects the repair effect. When the metal plate is implanted and repaired, although the personalized customization technology based on the patient's own bone structure is relatively matur...

AI Technical Summary

Problems solved by technology

However, the current tissue engineering repair based on stem cell technology uses absorbable materials as scaffold materials, which absorb quickly and cannot provide good mechanical support. It can only repair defects less than 3cm, and cannot repair more than 4 tooth positions (greater than 3cm). defect

[0006] The difficulty in repairing mandibular defects lies in the restoration of the patient's appearance and masticatory function. Therefore, tissue engineering technology has special requirements for the shape, material and structure of the bracket and implant. There is no mature technology available in the field of mandibular repair for traumatic defects larger than 3cm

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