Application of Yixuanning granules in preparation of medicaments for treating insomnia

A technology of Yixuanning and granules, which is applied in drug combinations, pharmaceutical formulas, plant raw materials, etc., to achieve the effects of easy preservation, high sleep quality, and convenient administration

Inactive Publication Date: 2013-10-09
TONGHUA MAOXIANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Indications for the treatment of hyperactivity of liver yang and vertigo of qi and blood deficiency type, and its application in the preparation of insomnia medicine has not been reported

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0025] The application of Yixuanning granule as a medicine for treating insomnia; said Yixuanning granule is made of the following raw materials: Dannanxing 75g, Lycium barbarum 100g, pig Tieluo 75g, oyster (calcined) 100g, Poria cocos 100g, chrysanthemum flower 75g, cocklebur (fried) 100g, white peony 75g, bamboo 75g, scutellaria baicalensis 75g, hawthorn 50g, tangerine peel 75g. For the above twelve flavors, take pig iron powder, oysters, add appropriate amount of water, and cook for 2 hours, then add cocklebur, chrysanthemum, Dannanxing, Zhuru, and tangerine peel and continue to cook for three times, successively for 1, 1, and 0.5 hours, and then filter. After passing, the filtrates were combined, and the filtrate was concentrated to a clear paste with a relative density of 1.0-1.2 (80-90°C). The remaining scutellaria baicalensis, white peony root, poria cocos, hawthorn, medlar, etc. were decocted twice with water for 1 hour and 0.5 hours in turn, filtered in several times,...

experiment example

[0027] Clinical Trials

[0028] The drug test was carried out on 86 insomnia patients (as shown in the table below):

[0029] age gender 20-30 years old 30-40 years old 40-50 years old over 50 years old total male 3 7 11 23 44 female 5 6 13 18 42 total 8 13 24 41 86

[0030] The above 86 patients all had insomnia as the main symptom. In mild cases, it was difficult to sleep or easy to wake up after waking up, and insomnia after waking up. In severe cases, it was difficult to sleep all night. Palpitations, forgetfulness, restlessness, dreaminess and other symptoms. Among them, there were 44 males and 42 females; the age ranged from 20 to 62 years, with an average of 40.3 years; the course of disease ranged from 3 months to 6.5 years, with an average of 3.8 years; 24 cases took diazepam regularly, and 16 cases used other traditional Chinese medicines.

[0031] Dosage: Take Yixuanning Granules orally, 1 bag at a time, 3 ...

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PUM

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Abstract

The invention relates to a new application of a traditional Chinese medicine preparation, namely an application of Yixuanning granules in preparation of medicaments for treating insomnia. The Yixuanning granules have the functions of tranquilizing liver and yang, lowering fire, clearing phlegm, nourishing blood, invigorating spleen, expelling wind and clearing away heat, and can be used for treating hyperactivity of liver yang and qi and blood deficiency type vertigo; and simultaneously, the effect on treating insomnia is also great. The Yixuanning granules are the granules and have the characteristics of convenience in carrying, convenience in administration, good taste, easiness in preservation and stable active pharmaceutical ingredients. The Yixuanning granules are the traditional Chinese medicine preparation, and have the advantages of small side effects in the treatment on insomnia in comparison with western medicines, high sleep quality, no medicament dependence and the like. The clinical observation of 86 patients with insomnia, who take the Yixuanning granules, shows that the total effective rate is above 95.35%.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine preparation, that is, the application of Yixuanning granule as a medicine for treating insomnia. Background technique [0002] Insomnia is a common disease, also known as insomnia or "can't sleep", "can't lie down", "eyes can't go dark", refers to the disease that often can't get normal sleep. The severity of insomnia varies. In mild cases, it is difficult to fall asleep, in some cases it is difficult to fall asleep, in others it is easy to wake up after waking up, in some cases it is impossible to fall back asleep after waking up, and in some cases it is difficult to fall asleep all night. Insomnia can occur alone, and can also occur simultaneously with headaches, dizziness, palpitations, and forgetfulness. [0003] There are many medicines used in the treatment of insomnia at present, both Chinese and Western medicines have different curative effects. Western medicines have...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K9/16A61P25/20A61K33/26A61K35/56A61K35/618
Inventor 王茂祥贺天鹏于静涛
Owner TONGHUA MAOXIANG PHARMA
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