Veterinary ephedra, almond, gypsum and liquoric root granules and preparation method thereof

A technology of Maxing Shigan and granules, which is applied in the field of Maxing Shigan granules and its preparation, which can solve the problems of coarse dosage form, affecting the quality of traditional Chinese veterinary medicine and clinical treatment effect, and low bioavailability

Inactive Publication Date: 2013-11-27
ZHENGZHOU FUYUAN ANIMAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The currently used Maxing Shigan Powder has the disadvantages of large dosage, rough dosage form, poor appearance, etc., the active ingredients cannot be fully released, and the bioavailability is low, which seriously affects the quality of traditional Chinese veterinary medicine and clinical treatment effect, and cannot be uniformly mixed with pellet feed, Can not be directly added to drinking water

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Weigh 500 grams of gypsum, 100 grams of almonds, 100 grams of ephedra, and 100 grams of licorice, cut and clean the ephedra and licorice, wrap the gypsum, add ethanol-water (4:6) solution to extract and decoct twice, 40 minutes each time, add The amount of water is 6L, the decoction liquid is combined, filtered, concentrated to 300 grams, 300 grams of auxiliary materials are added, and granulated in a fluidized bed to obtain the granules of the present invention.

Embodiment 2

[0017] Weigh 600 grams of gypsum, 100 grams of almonds, 100 grams of ephedra, and 120 grams of licorice, cut and clean the ephedra and licorice, wrap the gypsum, add ethanol-water (2:8) solution to extract and decoct 4 times, 20 minutes each time, add The amount of water is 4L, the decoction is combined, filtered, concentrated to 400 grams, 400 grams of auxiliary materials are added, and granulated in a fluidized bed to obtain the granules of the present invention.

Embodiment 3

[0019] Weigh 500 grams of gypsum, 120 grams of almonds, 120 grams of ephedra, and 120 grams of licorice, cut and clean the ephedra and licorice, wrap the gypsum, add ethanol-water (3:7) solution to extract and decoct 4 times, 20 minutes each time, add The amount of water is 4.5L, the decoction liquid is combined, filtered, concentrated to 400 grams, 400 grams of auxiliary materials are added, and granulated in a fluidized bed to obtain the granules of the present invention.

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PUM

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Abstract

The invention discloses veterinary ephedra, almond, gypsum and liquoric root granules and a preparation method thereof. The ingredients of the granules comprise ephedra, almond, gypsum, liquoric root, a diluent, an adhesive, a sweeting agent and an anti-caking agent. According to the granules and the preparation method, the Chinese medicine ingredients are extracted by using a microwave assisted extraction method, the extract is prepared into liquid extract, then the liquid extract is pretreated to form liquor, and the liquor is granulated through a fluidized bed technique. The preparation method has a short flow and high production efficiency, the palatability of the veterinary ephedra, almond, gypsum and liquoric root granules is improved by adding the sweeting agent, the preparation process has high Chinese traditional medicine extraction efficiency, and the single dosage for an animal is reduced, so that the veterinary ephedra, almond, gypsum and liquoric root granules have the characteristics of no bitterness, convenience in administration and the like.

Description

technical field [0001] The invention relates to the field of veterinary drug preparations, in particular to Maxing Shigan Granules and a preparation method thereof; Background technique [0002] Maxing Shigan Decoction comes from "Treatise on Febrile Diseases" written by Zhang Zhongjing in the Eastern Han Dynasty. It is a traditional ancient prescription in my country. Because of its reasonable composition and remarkable curative effect, it has been valued by ancient medicine. According to the principle of pathogenic heat in the lungs, this prescription guides the method of clearing Qi and promoting the lungs, and uses gypsum as the king's medicine. Jiao, clearing away lung heat to calm asthma, almond bitterness, clearing lung and lowering qi to calm asthma, licorice to reconcile various medicines, mixed with almonds to relieve cough, it is an adjuvant drug, and it has the effect of clearing heat and relieving lung. It is suitable for patients with exogenous wind pathogens...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/736A61K9/16A61P11/00A61K33/06
Inventor 袁宝青王树槐李红娇赵新双
Owner ZHENGZHOU FUYUAN ANIMAL PHARMA
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