Selenium butyric acid inclusion agent and preparation method thereof

A technology of selenobutyric acid and mixture, which is applied in the direction of drug combination, pharmaceutical formula, sulfur/selenium/tellurium active ingredients, etc. It can solve the problems of not adapting to the weak body of patients, bad smell of fatty acids, and affecting the use effect, etc., to achieve inhibition Infiltration activity, obvious synergistic effect, effect of promoting digestive tract peristalsis

Inactive Publication Date: 2013-12-18
杨吉星
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the medicine has the following disadvantages, which seriously affect the use effect: (1), there are medicinal materials madder and gardenia with two tastes cold in nature and similar functions i

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0050] Embodiment: Take raw material by following formula ratio

[0051] 6 parts of ginseng, 13 parts of madder, 11 parts of wolfberry

[0052] Schisandra 4 parts Coix seed 15 parts Poria 9 parts

[0053] 12 parts of Radix Pseudostellariae, 0.00045 parts of Sodium Selenite.

[0054] production method:

[0055] (1) Ginseng, schisandra, Poria cocos, and heterophylla are mixed and pulverized according to the above formula ratio, extracted with 75% ethanol (6 times the amount) under reflux for 2 hours, repeated extraction once, filtered the alcohol extract for later use, and the medicinal residues are stored separately; ( 2) Mix and pulverize wolfberry, coix seed, and madder according to the above formula ratio, add the dregs after alcohol extraction, decoct twice (8 times the water), process for 1.5 hours each time, and filter the liquid medicine; (3) Alcohol extraction solution and water extraction solution are mixed and concentrated to 1:4, then add protease (Herbacillus glu...

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PUM

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Abstract

The invention discloses a selenium butyric acid inclusion agent. The selenium butyric acid inclusion agent is based on the traditional Chinese medicines including ginseng, rubia cordifolia, fructus lycii, schisandra chinensis, coix seed, wolfiporia extensa, pseudostellaria heterophylla, selenium and the like, prepared by using a modern microorganism fermentation technology, processed by using a cyclodextrin inclusion technology, comprises histone deacetylase in a brand-new chemical structure to function as a pure natural synergistic inhibitor, comprises the composite compounds of selenium, butyric acid, flavonoid, saponin and the like, and belongs to the tumor epigenetic regulation medicine using the novel anti-tumor action mechanism; different from a traditional tumor treatment medicine, the selenium butyric acid inclusion agent carries out saturation attack by taking the abnormal epigenetic inheritance of the cancer cell as the target, exerts the whole anti-tumor effect by inducing the immune monitoring and immune killing actions of the patient, and is capable of resisting oxidation, appropriate in taste and free from chemical pollution.

Description

technical field [0001] The invention relates to a medicine of "traditional Chinese medicine cyclodextrin inclusion complex containing selenium and fatty acid" and a preparation method thereof, in particular to a selenobutyric acid inclusion complex with anti-tumor and anti-oxidation functions and a preparation method thereof. Background technique [0002] Tumor is a major intractable disease that threatens human life and health. Scientists have found through in-depth studies on tumors that although the causes of tumor occurrence and development are very complex, they are all closely related to the abnormal activity of gene expression and gene expression products in the final analysis. At the same time, the deterioration of the primary and secondary tumor surrounding environment (such as angiogenesis, abnormal immune system function changes, etc.) formed by abnormal gene expression promotes the further development of malignant appearance of tumor cells, and produces prolifera...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61K47/48A61P35/00A61K33/04A61K47/69
Inventor 杨吉星杨京润
Owner 杨吉星
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