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Preparation method of perfluoro-2, 3-epoxy-2-methylpentane

A technology of methyl pentane and methyl, which is applied in the field of preparation of perfluoro-2,3-epoxy-2-methyl pentane, which can solve the problems of short reaction time, low reaction temperature and high cost

Active Publication Date: 2014-01-15
SINOCHEM LANTIAN +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

This method has high oxidation efficiency and short reaction time, but the preparation of oxides is difficult and dangerous, and the reaction temperature is low, and the cost of scale-up production is high

Method used

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Abstract

The invention discloses a preparation method of perfluoro-2, 3-epoxy-2-methylpentane. Perfluoro-2-methyl-2-pentene is adopted as a raw material to react with sodium hypochlorite to prepare perfluoro-2, 3-epoxy-2-methylpentane. The method has the advantages of mild reaction conditions, fast reaction rate, high reaction selectivity and high yield, etc. The prepared perfluoro-2, 3-epoxy-2-methylpentane can be used for synthesis of fluorine-containing alcohol compounds.

Description

technical field [0001] The invention relates to a preparation method of perfluoro-2,3-epoxy-2-methylpentane. Background technique [0002] Perfluoro-2,3-epoxy-2-methylpentane is an important intermediate in organic synthesis, which can be used to synthesize fluorine-containing alcohols, and can also react with other electrophiles, so that its molecular structure contains fluorine atom. Fluorine-containing compounds have attracted great attention due to their own biological activity and molecular pseudo-mimeticity in the human body, which makes perfluoro-2,3-epoxy-2-methylpentane have potential applications. The preparation method of perfluoro-2,3-epoxy-2-methylpentane is mainly obtained by oxidation of perfluoro-2-methyl-2-pentene. Patent SU666176, document Zhurnal Organiccheskoi Khimii., 22(1), 93 (1986), document Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya., 12, 2812 (1979) and document Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya., 91, 12 reported the p...

Claims

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Application Information

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IPC IPC(8): C07D303/08C07D301/03C07C49/167C07C45/28
CPCC07C45/58C07D301/03C07D303/48C07C49/167
Inventor 白占旗倪航方小青柳彩波
Owner SINOCHEM LANTIAN
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