Synergist used in 5% avermectin emulsion in water

A technology of abamectin and water emulsion, which is applied in the field of pesticides, can solve problems such as product failure, unstable preparation, and influence on drug efficacy, and achieve good synergistic effects, improved stability, and improved control effects

Active Publication Date: 2014-01-22
天津市华宇农药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] It is imminent to develop new formulations of environmentally friendly water-based abamectin. Water-emulsion is a new formulation suitable for abamectin. Compared with traditional emulsifiable oils, water in the water-emulsion replaces organic solvents that are toxic and harmful to the environment As a dispersion medium, it is environmentally friendly and safe, and the preparation has a high flash point, and is safe and convenient to store and transport. However, at the same time, because water is used as a dispersion medium and lacks oily substances, the affinity and spreading effect on pests and plant leaves are reduced, which affects the medicine. Adding methyl oleate can improve the efficacy of abamectin water emulsion, but because of its high freezing point (it will be partially solidified at about 0 degrees), generally coagulation at low temperature will lead to the precipitation of abamectin original drug, especially High content of abamectin in water emulsion is easier to precipitate under low temperature conditions, resulting in unstable preparation and product failure

Method used

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  • Synergist used in 5% avermectin emulsion in water
  • Synergist used in 5% avermectin emulsion in water
  • Synergist used in 5% avermectin emulsion in water

Examples

Experimental program
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Effect test

Embodiment 1

[0040] Embodiment 1: (add 5% synergistic abamectin aqueous emulsion of 10% palm oil C8-C10 methyl ester synergist)

[0041]

Embodiment 2

[0042] Embodiment 2: (add 5% synergistic abamectin aqueous emulsion of 30% palm oil C8-C10 methyl ester synergist)

[0043]

Embodiment 3

[0044] Embodiment 3: (add 5% synergistic abamectin aqueous emulsion of 5% palm oil C8-C10 methyl ester synergist)

[0045]

[0046] Biologically active example

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Abstract

The invention relates to a synergist used in 5% high-content avermectin emulsion in water. The synergist is a mixture of palm oil methyl methyloctanoate and palm oil methyl methyldecanoate, wherein the content of palm oil methyl methyloctanoate is 50-58% by weight and the content of palm oil methyl methyldecanoate is 42-50%. The synergist helps to keep the stability of the avermectin emulsion in water and enables the avermectin emulsion in water to give full play to effect. According to the 5% avermectin emulsion in water prepared by using the synergist, the palm oil C8-C10 methyl esters have extremely good synergy effect and help to improve the stability of the 5% high-content avermectin emulsion in water; and no avermectin is precipitated when the 5% high-content avermectin emulsion in water returns to form at normal temperature after subjected to cold storage at 0 DEG C or refrigerated at a low temperature. The synergist helps to greatly improve the control effect on insects after the synergist-containing 5% high-content avermectin emulsion in water is applied according to a conventional application method.

Description

technical field [0001] The invention relates to the technical field of pesticides, in particular to an improvement technology of an avermectin aqueous emulsion dosage form. Background technique [0002] Abamectin is a class of 16-membered macrolide compound with insecticidal, acaricidal and nematicidal activities firstly developed by Satoshi Omura of Kitasato University in Japan and Merck Company of the United States. It is produced by Streptomyces avermitilis Produced by fermentation. Natural abamectin contains 8 components, mainly 4 kinds, namely A1a, A2a, B1a and B2a, the total content of which is ≥80%; the corresponding 4 homologues with smaller proportions are A1b, A2b, B1b and B2b , its total content ≤ 20%. Currently commercially available abamectin pesticides use abamectin as the main insecticidal component (Avermectin B1a+B1b, wherein B1a is not less than 90% and B1b is not more than 5%), and is calibrated by the content of B1a. Since abamectin entered my country'...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N25/22A01N43/90A01P7/02A01P7/04A01P5/00
Inventor 张毅超董宝库
Owner 天津市华宇农药有限公司
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