6results about How to "Will not precipitate" patented technology

The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to an indissolvable drug nano mixed micelle carrier system and a preparation method thereof. The carrier system has high drug loading capacity and high stability, and can avoid degradation of active ingredients caused by long-time placement; the targeting property is high, so that toxicity reduction and synergism are facilitated; meanwhile, the preparation method is simple, convenient and easy to operate, short in process time and high in stability, and continuous production of micelles can be realized.

This invention discloses an industrial-scale chemical preparation method for 1,2-di fatty acid glycerides, comprising the following steps: (A) acetone glycerol is protected with a silyl ether protecting agent and purified by crystallization to obtain intermediate 1; (B) intermediate 1 undergoes a depropionyl protecting group reaction and crystallization to obtain intermediate 2; (C) intermediate 2 undergoes an esterification reaction and crystallization and adsorption to obtain intermediate 3; (D) intermediate 3 undergoes a desilyl ether protection reaction and recrystallization to obtain 1,2-di fatty acid glycerides. This invention, through crystallization purification under different conditions, avoids the disadvantages of traditional chemical methods for preparing 1,2-di fatty acid glycerides, such as the need for multiple column chromatography purification steps, low yield, and difficulty in industrialization. This method features mild operating conditions, high purity, and is easily scalable for large-scale industrialization.

The present application relates to a kind of not to precipitate long-acting superhigh flame-retardant efficiency propylene flame retardant, including flame retardant T-DOPO and polybucum, the content of flame retardant T-DOPO is 50%-90%, the content of polybucum is 10%-50%, by the flame retardant in the present application is added into propylene material, propylene can reach B1 grade flame-retardant effect, and propylene is stronger in the process of spinning, and inorganic salt crystal cannot be precipitated.

The application provides a method and system for natural evaporation crystallization of rare earth chlorides, and relates to the technical field of rare earth chlorides, which comprises the following steps: adjusting the pH value of a rare earth chloride solution to 5.0-7.5, and filtering and removing impurities after clarification; performing natural evaporation concentration on the rare earth chloride solution after impurity removal at the pH value to obtain a saturated rare earth chloride solution; and performing natural crystallization on the saturated rare earth chloride solution to precipitate rare earth chloride crystals. By using the method provided by the application, high-quality rare earth chloride crystals can be prepared in a relatively safe and environmentally friendly manner under the premise of greatly reducing evaporation energy consumption.

The application provides a degradable composite film, a preparation method thereof and food packaging, and belongs to the field of biodegradable polymer materials. The application is modified by taking polylactic acid as a main body to prepare a composite film with a multilayer structure; the tensile strength of the composite film is 40-50 MPa, the elongation at break is 30-66%, the tensile strength retention rate is 85-95%, the elongation at break retention rate is 80-90%, the mechanical property is excellent, the composite film has high barrier property and anti-aging property to oxygen and water vapor in the air, and the stability and service life of the composite film are improved. The composite film is applied to food packaging, so that the food in the packaging is kept fresh and dry, and the polyethylene glycol in the composite film does not occur precipitation after long-time use, and the composite film has excellent stability.

The invention provides a light emitting diode chip and a preparation method thereof, and belongs to the technical field of semiconductors. The light-emitting diode chip comprises an N-type semiconductor layer, an active layer and a P-type semiconductor layer which are stacked in sequence; the P-type semiconductor layer comprises a non-doped sub-layer and a doped sub-layer which are stacked together, the doped sub-layer comprises a first high-temperature phase layer, a second high-temperature phase layer and a third high-temperature phase layer which are stacked in sequence, and precursor materials of the non-doped sub-layer and the doped sub-layer are TEGa. According to the invention, the crystallization quality can be ensured, and the high doping concentration can also be ensured.