Deformable soft capsule
A soft capsule and capsule shell technology is applied in the directions of capsule delivery, medical preparations with non-active ingredients, and drug delivery, which can solve the problems of inability to change shape, large dosage form, and poor taking compliance, and achieve the effect of improving taking compliance.
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[0012] The present invention will be further described below in conjunction with the accompanying drawings.
[0013] like figure 1 As shown, a deformable soft capsule includes: a capsule shell 1 and a drug core 2 contained in the capsule shell 1, and the feature is that the shape of the capsule shell 1 has plasticity.
[0014] The composition of the capsule shell 1 includes gelatin, plasticizer and water, and the weight ratio of gelatin dry product, plasticizer dry product and water is 1:2.0-2.5:1.
[0015] The plasticizer is glycerin, sorbitol, a mixture of glycerol and sorbitol, or propylene glycol.
[0016] An isolation layer 3 for preventing the drug core 2 from dissolving the capsule shell 1 is arranged between the capsule shell 1 and the drug core 2 .
[0017] The isolation layer 3 is a plastic stomach-soluble isolation layer or a plastic erosion type isolation layer, and the components of the isolation layer 3 include hydroxypropyl cellulose, methyl cellulose, cellulo...
PUM
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Abstract
Description
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Application Information
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