A kind of medicinal syrup for treating infantile wind-heat and common cold and preparation method thereof

A wind-heat cold and syrup technology is applied in the field of medicinal syrup for treating wind-heat cold in children and the preparation field thereof, which can solve the problems of children's refusal to take it, toxic and side effects, poor taste, etc. The effect of improving the taste of the drug

Active Publication Date: 2021-08-03
JUMPCAN PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The types and contents of the active ingredients in the composition are not clear, and due to the volatile oil contained in the preparation process, the taste is poor, and the compliance of children to take it is low
Another example is the common antipyretic medicine on the market, which is made of cinnabar, orange red, Chuan Fritillaria, Dannanxing, Qianhu, Scrophulariae, etc., but cinnabar contains a lot of metal mercury, which has great effects on the body. Toxic and side effects, especially for children's growth and development
Shuanghuanglian oral liquid is also commonly used to treat wind-heat and cold, but its taste is bitter, and most children refuse to take it

Method used

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  • A kind of medicinal syrup for treating infantile wind-heat and common cold and preparation method thereof
  • A kind of medicinal syrup for treating infantile wind-heat and common cold and preparation method thereof
  • A kind of medicinal syrup for treating infantile wind-heat and common cold and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Example 1 Medicinal syrup and preparation method for treating wind-heat-cold in children

[0036] The drug syrup is: 80 parts of forsythia, 60 parts of light tempeh, 40 parts of mint, 40 parts of Nepeta, 30 parts of gardenia, 30 parts of rhubarb, 60 parts of Artemisia annua, 40 parts of red peony, 28 parts of betel nut, 60 parts of Magnolia bark, 60 parts of Scutellaria baicalensis, 60 parts of pinellia, 40 parts of Bupleurum, 30 parts of licorice (which contains 0.0027mg / ml of β-pinene, 0.0067mg / ml of menthol, 0.91mg / ml of forsythin , 0.98mg / ml of geniposide). As well as high fructose syrup, methylparaben, hydroxypropyl-beta-cyclodextrin, blueberry flavor.

[0037] The preparation method of described syrup is:

[0038] (1) Add forsythia, peppermint, Nepeta, Bupleurum and decoct with 4 times of water for 4 hours, extract volatile oil, volatile oil is clathrated with hydroxypropyl-β-cyclodextrin to obtain volatile oil inclusion compound, and the dregs are used for late...

Embodiment 2

[0060] Example 2 Drug syrup and preparation method for treating children with wind-heat and cold

[0061] The drug syrup is: 90 parts of forsythia, 70 parts of light tempeh, 50 parts of mint, 50 parts of Nepeta, 40 parts of gardenia, 40 parts of rhubarb, 70 parts of Artemisia annua, 50 parts of red peony, 35 parts of betel nut, 70 parts of Magnolia bark, 70 parts of Scutellaria baicalensis, 70 parts of pinellia, 50 parts of Bupleurum, 40 parts of licorice (after testing, it contains 0.018mg / ml of β-pinene, 0.196mg / ml of menthol, 3.07mg / ml of Forsythin, 2.93mg / ml geniposide, 0.0189mg / ml limonene, the detection method is the same as in Example 1); and glycyrrhizin, benzoic acid, hydroxypropyl-β-cyclodextrin, lemon essence.

[0062] The preparation method of described syrup is:

[0063] (1) Forsythia, peppermint, Nepeta, and Bupleurum are decocted with 6 times of water for 2.5 hours, and the volatile oil is extracted. The volatile oil is clathrated with hydroxypropyl-β-cyclodext...

Embodiment 3

[0066] Example 3 Medicinal syrup and preparation method for treating wind-heat-cold in children

[0067] The drug syrup is: 88.8 parts of forsythia, 66.6 parts of light tempeh, 44.4 parts of mint, 44.4 parts of nepeta, 37.8 parts of gardenia, 37.8 parts of rhubarb, 66.6 parts of Artemisia annua, 44.4 parts of red peony, 33.4 parts of betel nut, 66.6 parts of Magnolia officinalis, 66.6 parts of Scutellaria baicalensis, 66.6 parts of pinellia, 44.4 parts of Bupleurum, 37.8 parts of licorice (after testing, it contains 0.006mg / ml of β-pinene, 0.064mg / ml of menthol, 0.72mg / ml of Forsythin, 1.38mg / ml geniposide, the detection method is the same as in Example 1), sucrose, potassium sorbate, hydroxypropyl-β-cyclodextrin, and orange essence.

[0068] The preparation method of described syrup is:

[0069] (1) Forsythia, peppermint, Nepeta, and Bupleurum are decocted with 5 times of water for 3 hours, and the volatile oil is extracted. The volatile oil is clathrated with hydroxypropyl-...

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Abstract

The invention provides a traditional Chinese medicine composition, in particular to a medicinal syrup for treating wind-heat common cold in children, wherein each ml of syrup comprises 0.0024-0.02 mg of β-pinene, 0.0050-0.2 mg of menthol, 0.068-3 mg of continuous Aromain and 0.64-5mg of gardeniside, the syrup raw materials include forsythia, light tempeh, mint, nepeta, gardenia, rhubarb, artemisia, red peony, betel nut, magnolia, skullcap, pinellia, bupleurum , Licorice. The syrup has clear active ingredients and stable quality. In the preparation process, some traditional Chinese medicines are steamed and assisted by microwave extraction, which improves the efficiency and curative effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine and a preparation method thereof, in particular to a medicinal syrup for treating children with wind-heat and cold and a preparation method thereof Background technique [0002] Cold is a common exogenous disease, often caused by feeling exogenous pathogens. The main clinical features are fever, nasal congestion, runny nose, sneezing, and coughing. The disease can occur throughout the year, and often occurs in sudden climate change and winter and spring seasons. It is the most common disease in pediatrics. Traditional Chinese medicine believes that a cold is caused by experiencing wind-cold, wind-heat, summer-dampness and timely evils. Because children's lungs are delicate, spleen is often insufficient, and their air is timid. [0003] Pediatric wind-heat-cold is characterized by severe fever, mild aversion to cold, aversion to wind, sweating or less sweating, headache, nasal congestion, runny n...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/00A61K36/889A61K9/00A61K47/26A61K47/06A61K47/10A61K47/69A61P11/00
CPCA61K9/0095A61K36/233A61K36/282A61K36/48A61K36/484A61K36/534A61K36/538A61K36/539A61K36/575A61K36/634A61K36/65A61K36/708A61K36/71A61K36/744A61K36/8888A61K36/889A61K47/06A61K47/10A61K47/26A61K2236/331A61K2236/39A61K2236/53A61K47/6951A61P11/00A61K2300/00
Inventor 曹龙祥田刚李昌龙李超朱法根蔡虎
Owner JUMPCAN PHARMA GRP
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