Joint inspection kit for pregnant woman premature birth fetus fibronectin and phosphorylation insulin-like growth factor binding protein-1

A fibronectin, premature fetus technology, applied in biological testing, material testing products, biological material analysis, etc., can solve problems such as cumbersome operations, increased risk of premature birth, uterine contractions or infection in pregnant women, and avoid uterine contractions. , Improve the positive predictive value and negative predictive value, suitable for large-scale promotion and application

Inactive Publication Date: 2014-01-29
无锡博慧斯生物医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At present, most of the above-mentioned clinical diagnosis of premature birth is carried out separately; this kind of treatment increases the cumbersomeness of the operation, and at the same time, because of the need to frequently sample pregnant women, it will stimulate the chances of uterine contractions or infection in pregnant women, thereby increasing the risk of premature birth. risk

Method used

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  • Joint inspection kit for pregnant woman premature birth fetus fibronectin and phosphorylation insulin-like growth factor binding protein-1
  • Joint inspection kit for pregnant woman premature birth fetus fibronectin and phosphorylation insulin-like growth factor binding protein-1
  • Joint inspection kit for pregnant woman premature birth fetus fibronectin and phosphorylation insulin-like growth factor binding protein-1

Examples

Experimental program
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Effect test

Embodiment 1

[0026] A kit for combined detection of fibronectin and phosphorylated insulin-like growth factor-binding protein-1 in premature fetuses of pregnant women, comprising a bottom plate 9, and a nitrocellulose membrane 7 is arranged on one side of the bottom plate 9;

[0027] The front end of the nitrocellulose membrane 7 is provided with a bonding pad 1, and the rear end of the bonding pad 1 is provided with several arrow labels 2, and the first opaque protective pad 3 is arranged behind the arrow label 2; the first opaque protective pad 3 is arranged behind the first Detection line 4, quality control line 6 is set behind the first detection line 4;

[0028] The rear end of the nitrocellulose membrane 7 is provided with a second opaque protective pad 8 .

[0029] A second detection line 5 is also arranged between the first detection line 4 and the quality control line 6 .

[0030] The binding pad 1 contains an anti-human phosphorylated IGFBP-1 colloidal gold-labeled antibody and ...

Embodiment 2

[0033] A kit for combined detection of fibronectin and phosphorylated insulin-like growth factor-binding protein-1 in premature fetuses of pregnant women, comprising a bottom plate 9, and a nitrocellulose membrane 7 is arranged on one side of the bottom plate 9;

[0034] The front end of the nitrocellulose membrane 7 is provided with a bonding pad 1, and the rear end of the bonding pad 1 is provided with several arrow labels 2, and the first opaque protective pad 3 is arranged behind the arrow label 2; the first opaque protective pad 3 is arranged behind the first Detection line 4, quality control line 6 is set behind the first detection line 4;

[0035] The rear end of the nitrocellulose membrane 7 is provided with a second opaque protective pad 8 .

[0036] The joint detection kit consists of two joint detection kits with the same structure placed side by side in the same box.

[0037] One of the parallel binding pads 1 contains an anti-human phosphorylated IGFBP-1 colloida...

Embodiment 3

[0039] A kit for combined detection of fibronectin and phosphorylated insulin-like growth factor-binding protein-1 in premature fetuses of pregnant women, comprising a bottom plate 9, and a nitrocellulose membrane 7 is arranged on one side of the bottom plate 9;

[0040] The front end of the nitrocellulose membrane 7 is provided with a bonding pad 1, and the rear end of the bonding pad 1 is provided with several arrow labels 2, and the first opaque protective pad 3 is arranged behind the arrow label 2; the first opaque protective pad 3 is arranged behind the first Detection line 4, quality control line 6 is set behind the first detection line 4;

[0041] The rear end of the nitrocellulose membrane 7 is provided with a second opaque protective pad 8 .

[0042] The binding pad 1 on one side of the bottom plate 9 contains an anti-human phosphorylated IGFBP-1 colloidal gold-labeled antibody, and the corresponding first detection line 4 is coated with an anti-human phosphorylated I...

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Abstract

The invention relates to a joint inspection kit for pregnant woman premature birth fetus fibronectin and phosphorylation insulin-like growth factor binding protein-1, and belongs to the technical field of inspection kits. The kit comprises a substrate, wherein a nitrocellulose membrane is arranged on one side of the substrate; a binding pad is arranged at the front end of the nitrocellulose membrane; a plurality of arrow tags are arranged at the rear end of the binding pad; a first non-transparent protection pad is arranged behind the arrow tags; a first detection line is arranged behind the first non-transparent protection pad; a mass control line is arranged behind the first detection line; a second first non-transparent protection pad is arranged at the rear end of the nitrocellulose membrane. A second detection line is further arranged between the first detection line and the mass control line. The kit is simple and convenient to apply, can be used for further improving the accuracy in premature birth diagnosis, and is applicable to large-scale popularization and application as joint inspection result provides a powerful basis for next accurate treatment.

Description

technical field [0001] The invention relates to a kit for combined detection of fibronectin and phosphorylated insulin-like growth factor binding protein-1 in pregnant women and premature fetuses, and belongs to the technical field of detection kits. Background technique [0002] Birth between 28 weeks and less than 37 weeks of gestation is called premature birth. Preterm birth is divided into two types: spontaneous premature birth and therapeutic premature birth. Spontaneous premature birth includes preterm delivery and preterm premature rupture of membranes. Therapeutic premature birth is a pregnancy complication or complication that requires early termination of pregnancy; among them, spontaneous Preterm births account for the vast majority. [0003] At present, there are mainly the following methods for clinical diagnosis of premature birth: [0004] 1) Cervical assessment: measure the length and structural changes of the cervix. Generally, when the length of the cervi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/68G01N33/531
CPCG01N33/6803G01N33/558G01N2800/368
Inventor 时振华刘岩韦彦余
Owner 无锡博慧斯生物医药科技有限公司
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