Composition for treating fundus macular oedema and application of composition to treating eye diseases

A macular edema and composition technology, applied in the field of medicine, can solve problems such as increase, adverse effects, low bioavailability, etc., and achieve the effects of reducing macular edema and inflammation, stabilizing intraocular pressure, and improving liver function

Active Publication Date: 2014-02-12
陈井然
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, after systemic treatment, the oral administration of drugs for the treatment of retinal diseases has a low bioavailability of active components entering the retina
In addition, the active ingredient needs to reach a certain amount in the retina to exert a therapeutic effect. For this reason, the oral dosage needs to be increased. If the drug has side effects, when the dosage is large, it may cause adverse effects on the whole body

Method used

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  • Composition for treating fundus macular oedema and application of composition to treating eye diseases
  • Composition for treating fundus macular oedema and application of composition to treating eye diseases
  • Composition for treating fundus macular oedema and application of composition to treating eye diseases

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Embodiment Construction

[0026] This embodiment provides a composition for treating fundus macular edema, which needs to contain (a) polyphenolic compound, (b) lipoic acid, dihydrolipoic acid, or its salt or amide compound, (c) pan quinone or panthenol, (d) docosahexaenoic acid or its ethyl ester compound and / or eicosapentaenoic acid or its ethyl ester compound.

[0027] Polyphenols are one or more proanthocyanidin polymers. At the same time, the combined mixture may include the following vitamins: one of A, B, C, D, E or a mixture of several vitamins. The component may further contain minerals, such as oxides of zinc, magnesium, or salts thereof, either alone or in combination. In certain instances, the composition contains a pharmaceutically acceptable carrier substance.

[0028] In a specific example, the inventive components are 25-800 mg of anthocyanin polymer, 25-1800 mg of lipoic acid, 0-2000 mg of docosahexaenoic acid or its ethyl ester compound and / or eicosanoid Carbapentaenoic acid or it...

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Abstract

The invention discloses a composition for treating fundus macular oedema and application of the composition in treatment of eye diseases and belongs to the technical field of medicines. The composition for treating the fundus macular oedema comprises the following components in percentage by weight: 0.4-71% of (a) polyphenolic compounds, 0.6-93% of (b) lipoic acid, dihydrolipoic acid, lipoic acid salt or lipoamide, 0-97% of (c) ubiquinone or panthenol and 0-87% of (d) docosahexaenoic acid or ethyl ester thereof and / or timnodonic acid or ethyl ester thereof. The composition can be used for improving patient visual acuity, stabilizing intraocular pressure and reducing various ocular inflammations such as the fundus macular oedema. By means of the composition for treating the fundus macular oedema and a treatment method, the fundus macular oedema can be prevented, stabilized, controlled or treated and the fundus health can be enhanced; in the meantime, the intraocular pressure can be stabilized, the vision can be maintained or improved, various eye diseases or macular oedema and inflammation which are caused by eye operations can be reduced; the diabetic complication is also treated, the blood microcirculation is promoted and the liver function is improved.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a composition for treating eye diseases and the application of the composition in treating eye diseases. Background technique [0002] At present, the main diseases causing blindness and visual impairment in Chinese adults, especially the elderly, are cataract, senile fundus maculopathy, myopic fundus maculopathy, and glaucoma. The complications of diabetes are reflected in the eyes in a considerable number of people, leading to blurred vision and even blindness. In Europe and America, the main diseases causing blindness are senile fundus macular degeneration, glaucoma, cataract, and diabetic retinopathy. Arthritis, heart disease and vision loss are the three major diseases that directly cause difficulties in daily life and activities among people over 70 years old. According to projections, by 2020, nearly six million Americans will be blind or have low vision. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/385A61K31/353A61K31/122A61K31/20A61K31/202A61K31/07A61K31/51A61K31/714A61K31/525A61K31/4415A61K31/375A61K31/59A61K31/355A61P27/02A61P27/06A61P7/10A61P9/10
Inventor 陈井然马祝宁
Owner 陈井然
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