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Method for measuring retinal blood vessel diameter and thickness of vessel wall

A technology for retinal blood vessels and blood vessel walls, applied in the field of measurement, can solve problems such as easy to cause errors, low accuracy of retinal blood vessel methods, and inability to obtain retinal blood vessel wall thickness data, so as to ensure repeatability and accuracy, avoid Mydriatic effect

Active Publication Date: 2014-02-19
衢州市人民医院
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Problems solved by technology

[0003] In order to overcome the shortcomings of the existing methods for measuring retinal blood vessels that are not accurate enough to easily lead to errors and cannot obtain retinal vessel wall thickness data, the present invention provides a retinal vessel wall measurement method with high accuracy and capable of obtaining retinal vessel wall thickness data. Vessel Diameter and Vessel Wall Thickness Methods

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  • Method for measuring retinal blood vessel diameter and thickness of vessel wall
  • Method for measuring retinal blood vessel diameter and thickness of vessel wall
  • Method for measuring retinal blood vessel diameter and thickness of vessel wall

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[0020] Reference Figure 1-3 , Further explain the present invention:

[0021] A method for measuring retinal blood vessel diameter and blood vessel wall thickness, using SD-OCT scanning system for measurement, setting the scanning light source wavelength to 870nm, fundus confocal laser imaging wavelength to 820nm, scanning speed to 40000A-Scan / sec, axial The resolution is 5μm, the lateral resolution is 6μm, and the scanning depth is 2.0mm. In this embodiment, the Spectralis SD-OCT scanning system of Heidelberg, Germany is used.

[0022] The measurement method includes the following steps:

[0023] 1) Locating through the concentric circle positioning ring of the SD-OCT scanning system, select all the retinal blood vessels in the area 0.5-1.0 times the diameter of the optic disc from the edge of the optic disc as the measurement object;

[0024] 2) Adjust the direction of the scan marking line to make the scan line perpendicular to the running direction of the positioning blood vess...

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Abstract

Disclosed is a method for measuring the retinal blood vessel diameter and thickness of a vessel wall. The method is characterized by including: adopting an SD-OCT (spectral domain optical coherence tomography) scanning system for measurement and selecting all the retinal blood vessels in an area with the distance apart from the edge of an optical disc 0.5-1.0 times of the diameter of the optical disc as measuring objects through the SD-OCT system; allowing a scanning line to be perpendicular to the running direction of a positioning blood vessel to acquire a cross section figure of the retinal blood vessels; magnifying the scanned cross section figure of the blood vessels; moving a scale ruler to measure inner diameter and outer diameter of each blood vessel, wherein the thickness of the vessel wall=(the outer diameter-the inner diameter) / 2; calculating the central retinal artery equivalent Wt; taking the central retinal artery equivalent Wt=(0.87Wa<2>+1.01Wb<2>-0.22WaWb-10.73)<1 / 2> as a diagnostic basis. The method has the advantages of being free of damage, non-invasive, free of mydriasis and high in measurement precision.

Description

Technical field [0001] The invention relates to a measuring method, in particular to a method for measuring the diameter of the retinal blood vessel and the thickness of the blood vessel wall. Background technique [0002] Retinal blood vessels are small blood vessels, which are similar to the terminal blood vessel structure and physiological function of the heart, brain, kidney and other important organs. Therefore, the change of retinal blood vessel diameter can reflect the physiological and pathological changes of other blood vessels and their organs and tissues. It has been proved that retinal artery stenosis is related to the occurrence of diabetes and coronary heart disease, and the expansion of retinal vein is related to the occurrence and development of diabetes and stroke. Retinal blood vessels are also the only vascular system that can be directly observed and measured in the human body, and therefore have an irreplaceable auxiliary diagnostic status. Many epidemiologic...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/107
Inventor 童毓华
Owner 衢州市人民医院
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