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A kind of preparation and application thereof with the effect of preventing and treating acne

A technology of efficacy and preparation, applied in the direction of medical preparations containing active ingredients, skin care preparations, organic active ingredients, etc., can solve the problems of ineffective acne prevention and other problems

Active Publication Date: 2016-06-29
SHAANXI HUIKANG BIO TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In this case, it cannot be effective in the prevention of acne

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Weigh 8 parts of rhododendron, 4 parts of dipeptide, and 4 parts of twenty-peptide; add 80 parts of water and 100 parts of ethanol into the reactor, stir and heat up to 35°C, add 1.0 part of sulfuric acid, keep warm for 48 hours, and distill under reduced pressure The solvent was removed to give a white powder after purification.

Embodiment 2

[0037] Weigh 18 parts of rhododendron, 4 parts of tripeptide, 2 parts of tetrapeptide, 3 parts of ten peptide, 5 parts of fifteen peptide, 5 parts of hexapeptide, 2 parts of dipeptide; PEG40080 parts, PEG100100 parts Add it into the reactor, stir and raise the temperature to 80°C, add 1.0 part of lipase, keep it warm for 18 hours, distill off the solvent under reduced pressure, and obtain a white powder after purification.

Embodiment 3

[0039] Weigh 10 parts of rhododendron, 2 parts of dipeptide, 4 parts of tripeptide, 2 parts of tetrapeptide, and 4 parts of twenty-peptide; add 80 parts of carbitol and 100 parts of ethanol into the reactor, stir and heat up to 35 ℃, add 1.0 parts of potassium hydroxide, keep warm for 26 hours, distill off the solvent under reduced pressure, and obtain a white powder after purification.

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PUM

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Abstract

The invention provides an azelaic acid oligopeptide preparation with effects of efficiently preventing and treating acnes and an application thereof in medical cosmetic. The preparation is synthesized from azelaic acid and oligopeptide under the effect of a catalyst. The azelaic acid oligopeptide synthesized by the invention has the characteristics of being good in water solubility, and significant in effect of preventing and treating acnes, low in side effect and the like. The cosmetic containing azelaic acid oligopeptide prepared by the preparation can be the dosage forms such as stoste, water aqua, facial mask, cream dew, liquid makeup, hair gel, essence and the like. The cosmetic is compounded by the azelaic acid oligopeptide and matrix. A lot of clinical tests prove that the medical cosmetic disclosed by the invention has the characteristics of being good in prevention and treatment of the acnes on the skin of a human body, good in nutrient, small in side effect and the like.

Description

technical field [0001] The invention belongs to the intersection field of traditional Chinese medicine technology, chemical synthesis technology and cosmetics. It relates to the preparation of a high-efficiency acne prevention and treatment preparation and its application in cosmetics and medicines. Background technique [0002] Everyone has a love for beauty, especially boys and girls who have reached puberty, they always hope to show their beauty to their relatives, friends and colleagues. However, almost everyone in the world has been troubled by acne more or less. [0003] The occurrence of acne is mainly closely related to factors such as excessive sebum secretion, pilosebaceous gland duct blockage, bacterial infection and inflammatory response. After entering puberty, the level of androgen in the human body, especially testosterone, increases rapidly, which promotes the development of sebaceous glands and produces a large amount of sebum. At the same time, abnormal ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/64A61K8/36A61K38/00A61P17/10A61Q19/00A61K31/194
Inventor 李想张卫红史钰潘美玲唐兴宇鲁朝纲
Owner SHAANXI HUIKANG BIO TECH CO LTD