Natural pharmaceutical composition, and preparation method and application thereof
A technology of natural medicines and compositions, which is used in drug combinations, pharmaceutical formulations, antitumor drugs, etc.
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[0029] The first step: preparation of various extracts
[0030] (1) Preparation of Coptis cinnamon decoction concentrated extract
[0031] According to the compatibility ratio of 1-4:1, take Coptis chinensis and cinnamon, soak in distilled water for 1 hour, heat and decoct for 1 hour, filter with silk cloth, add distilled water to the medicine dregs, soak, decoct and filter in the same way, mix the two filtrates, heat and concentrate To a small volume, filter with an ultrafiltration membrane, and dry under reduced pressure to obtain the obtained product.
[0032] (2) Preparation of berberine
[0033] Coptidis rhizome is crushed, add ethanol to heat and reflux, suction filter, and repeat the above operation for the filter residue, combine the filtrate, recover ethanol under reduced pressure, add 1% acetic acid and heat to dissolve, suction filter, add concentrated hydrochloric acid to the solution until cloudy, cool, suction filter, ice Wash twice with water and once with ace...
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