Natural pharmaceutical composition, and preparation method and application thereof

A technology of natural medicines and compositions, which is used in drug combinations, pharmaceutical formulations, antitumor drugs, etc.

Inactive Publication Date: 2014-03-26
张宗升
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that has the effect of alleviating diarrhea against cancer chemotherapy

Method used

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  • Natural pharmaceutical composition, and preparation method and application thereof

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Embodiment approach

[0029] The first step: preparation of various extracts

[0030] (1) Preparation of Coptis cinnamon decoction concentrated extract

[0031] According to the compatibility ratio of 1-4:1, take Coptis chinensis and cinnamon, soak in distilled water for 1 hour, heat and decoct for 1 hour, filter with silk cloth, add distilled water to the medicine dregs, soak, decoct and filter in the same way, mix the two filtrates, heat and concentrate To a small volume, filter with an ultrafiltration membrane, and dry under reduced pressure to obtain the obtained product.

[0032] (2) Preparation of berberine

[0033] Coptidis rhizome is crushed, add ethanol to heat and reflux, suction filter, and repeat the above operation for the filter residue, combine the filtrate, recover ethanol under reduced pressure, add 1% acetic acid and heat to dissolve, suction filter, add concentrated hydrochloric acid to the solution until cloudy, cool, suction filter, ice Wash twice with water and once with ace...

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Abstract

The invention relates to a natural pharmaceutical composition, and a preparation method and application thereof. The natural pharmaceutical composition is composed of 2-7 parts of coptis / cinnamon water decoction concentrated extract, 3-7 parts of berberine and 4-6 parts of cinnamaldehyde. The composition has favorable curative effect on cancer chemotherapy related diarrhoea.

Description

technical field [0001] The present invention relates to a natural medicine composition, more specifically to a natural medicine composition composed of coptis cinnamon decoction concentrated extract, berberine and cinnamaldehyde, a preparation method of the natural medicine composition and the natural medicine composition Use of the drug in the preparation of a medicament for reducing cancer chemotherapy-associated diarrhea. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs are cytotoxic anti-tumor drugs, which can cause diarrhea and other side effects when used alone or in combination. Diarrhea after tumor chemotherapy is also called chemotherapy-associated diarrhea. In recent years, with the advent an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61K9/48A61K9/20A61P1/12A61P35/00
Inventor 张宗升
Owner 张宗升
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