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Traditional Chinese medicine composition

A composition and technology of traditional Chinese medicine, applied in the field of preparing drugs for reducing cancer chemotherapy-related diarrhea, achieving the effects of convenience, high industrial applicability, and good curative effect

Inactive Publication Date: 2014-03-26
张宗升
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  • Description
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  • Application Information

AI Technical Summary

Problems solved by technology

[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that has the effect of alleviating diarrhea against cancer chemotherapy

Method used

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  • Traditional Chinese medicine composition

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Effect test

Embodiment approach

[0031] The first step: preparation of various extracts

[0032] (1) Preparation of concentrated extract of Andrographis ebony decocted in water

[0033] According to the compatibility ratio of 1-4:1, take Andrographis paniculata and black plum, soak in distilled water, heat and decoct, filter, add distilled water to the dregs, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate, and use an ultrafiltration membrane Filter, dry under reduced pressure, that is.

[0034] (2) Preparation of andrographolide

[0035] Weigh an appropriate amount of Andrographis paniculata powder, pre-treat with enzymatic hydrolysis, soak in ethanol, filter, and recover ethanol to obtain extract, wash with petroleum ether, remove chlorophyll, extract the water layer with chloroform overnight, divide into water layer, chloroform layer and middle layer, and recrystallize the precipitate from the middle layer with ethanol to obtain crystals that are andrographolide.

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Abstract

The invention relates to a traditional Chinese medicine composition. The traditional Chinese medicine composition is composed of 2-3 parts of creat / dark plum water decoction concentrated extract, 7-9 parts of andrographolide and 5-8 parts of dark plum ethanol extract. The composition has curative effect on cancer chemotherapy related diarrhoea.

Description

technical field [0001] The present invention relates to a traditional Chinese medicine composition, more specifically to a traditional Chinese medicine composition composed of andrographis ebony decoction concentrated extract, andrographolide and ebony ethanol extract, a preparation method of the traditional Chinese medicine composition and the traditional Chinese medicine composition Use in preparing medicines for reducing cancer chemotherapy-associated diarrhea. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs are cytotoxic anti-tumor drugs, which can cause diarrhea and other side effects when used alone or in combination. Diarrhea after tumor chemotherapy is also called chemotherapy-associated ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/736A61P35/00A61P1/12A61K31/365
Inventor 张宗升
Owner 张宗升
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