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Pharmaceutical composition used for preventing primary tumor metastasis after exairesis

A primary tumor, surgical resection technology, used in antitumor drugs, drug combinations, active ingredients of phosphorus compounds, etc.

Inactive Publication Date: 2014-04-09
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Surgical resection is the preferred treatment option for primary tumors, which do not require "anticancer drugs"; when drugs are needed to prevent metastatic spread of tumors after surgery, there are currently no such drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0025] Tablet preparation of combination medicine: Active ingredients such as oleanane-type ginsenoside Rg3 (100mg), periostin (10mg), metapristone (2mg), aspirin (25mg), and lysine (10mg) will be prepared Mixed with microcrystalline cellulose (100 mg), and modified corn starch (100 mg), prepared into granules and sieved. The sieved granules were mixed with modified corn starch (100 mg) and magnesium stearate (1 mg), and the mixture was compressed into tablets.

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PUM

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Abstract

The invention provides a pharmaceutical composition used for comprehensive prevention of primary tumor metastasis after exairesis. The pharmaceutical composition is composed of five kinds of drugs, which are capable of increasing body internal tumor immune functions, inhibiting marrow internal circulation tumor cell activity, inhibiting adhesion and implantation of circulating tumor cells in blood onto tunica elastica interna, preventing aggregation of circulating tumor cells in blood vessels, and strengthening tissue matrix structures respectively. Each of the five drug is capable of controlling a different point related to tumor metastasis. Optimized combination of the five drugs is capable of preventing tumor cells from metastasis after exairesis effectively and safely.

Description

technical field [0001] The present invention relates to an optimized combination of five types of drugs in order to comprehensively and safely prevent or adjuvantly treat tumor re-metastasis (or recurrence) in mammalian patients after surgical resection of the primary tumor. Background technique [0002] The defect of existing technology and the beneficial effect of the present invention: over the past 50 years, the death rate of other major diseases (heart disease etc.) has declined substantially (>60%), but cancer death rate has only reduced about 5%, wherein most Most died of tumor metastasis. The death caused by tumor metastasis is currently a global economic, social, and technological problem that needs to be solved urgently. The research and development of traditional mainstream "anticancer drugs" followed a slow and stupid route of "fighting cancer after cancer metastasis", with little effect. The current "effective" chemotherapy drugs can not effectively control...

Claims

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Application Information

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IPC IPC(8): A61K45/06A61K38/17A61P35/04
CPCA61K9/2059A61K31/167A61K31/198A61K31/40A61K31/405A61K31/415A61K31/567A61K31/616A61K31/663A61K31/704A61K33/42A61K36/074A61K36/21A61K36/75A61K38/17A61K45/06A61K2300/00
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