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1 results about "Periostin" patented technology
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Periostin (POSTN, PN, or osteoblast-specific factor OSF-2) is a protein that in humans is encoded by the POSTN gene. Periostin functions as a ligand for alpha-V/beta-3 and alpha-V/beta-5 integrins to support adhesion and migration of epithelial cells.
Use of sclerostin in the preparation of a preparation for preventing and treating hair loss
The present application belongs to the field of biomedical and cosmetic technology, and particularly relates to the application of periostin in the preparation of preparations for promoting the activity of hair follicle cells or for preventing and treating alopecia. The present application first discovers that periostin has the activity of regulating hair follicle papilla cells, hair matrix cells and outer root sheath cells, can promote the proliferation of hair follicle papilla cells, hair matrix cells and outer root sheath cells, improve the hair induction ability of hair follicle papilla cells, and promote the hair follicle cycle transformation, hair growth and thickening, and can be applied to the preparation of preparations for treating alopecia.
Owner:SOUTHERN MEDICAL UNIVERSITY