A magnetic separation device

Abstract

The invention discloses a magnetic separation device. The magnetic separation device comprises a base, a microwell plate, sliding grooves, a lifting bracket and magnetic block supporting strips, wherein the base is provided with a microwell plate fixing groove; the microwell plate is clamped in the microwell plate fixing groove and is horizontally arranged; the sliding grooves formed in the side edges of the base arranged below the microwell plate, the sliding grooves are parallelly arranged at intervals, and the interval between every two adjacent pipe arrays arranged on the microwell plate are in one-to-one correspondence; the lifting bracket is arranged on the base arranged below the microwell plate and is provided with magnetic block supporting strips which are parallel in an interval manner, one end of each magnetic block supporting strip is respectively clamped in the corresponding sliding groove, and the magnetic block supporting strips and the sliding grooves are in clearance fit; the magnetic block supporting strips are provided with magnetic block holes which are in one-to-one correspondence to a pipe-shaped container in the microwell plate, and each magnetic block hole is internally provided with an adaptive magnetic block. The magnetic separation device disclosed by the invention has the advantages that the magnetic blocks are finally driven to realize an upper-down movement through the upper-down movement of the lifting bracket, the magnetic blocks can stay on the different parts of the pipe-shaped container through the upper-down movement of the lifting bracket, and the controlled agglomeration and dispersion of magnetic particles are realized.

Description

technical field [0001] The invention relates to biomedical separation technology, in particular to a high-throughput fully automatic magnetic separation device. Background technique [0002] Magnetic particles have the advantages of high specific surface area, superparamagnetism, and easy surface modification. In the field of biomedicine, it is often necessary to separate magnetic particles. Commonly used methods include centrifugation, ion exchange, chemical purification, and magnetic separation. Among these commonly used separation methods, compared with centrifugation, ion exchange, and chemical purification, magnetic separation has the advantages of simple and fast operation, no corrosive and toxic reagents, and safer and more reliable advantages, so it has been widely used in the field of biomedicine. It has become more and more widely used and has become a commonly used method in routine biochemical experiments, such as nucleic acid extraction, gene sequencing, and imm...

AI Technical Summary

Problems solved by technology

[0004] Technical problem to be solved: Aiming at the deficiencies of the prior art, the present invention proposes a fully automatic magnetic separation device, which solves the problem that the magnetic beads in the traditional magnetic separation device in the prior art can only be placed in a single fixed position and in a single state. Form agglomeration leads to cumbersome operation of the magnetic separation device, high probability of cross-contamination, and poor controllability, and the devices mentioned in some existing patents that can adjust the agglomeration position of magnetic beads have the disadvantages of complex structure, bulky size, and inability to integrate

Images