Sampling and pre-treatment mixing device for clostridium difficile infected sample

Abstract

The invention belongs to the field of medical equipment and particularly relates to a sampling and pre-treatment mixing device for a clostridium difficile infected sample. The sampling and pre-treatment mixing device for the clostridium difficile infected sample comprises a storage bottle and a sampling device. The sampling and pre-treatment mixing device is characterized in that the storage bottle is internally provided glass beads; an ethanol storage device, and the sampling device with a suction device and a sampling spoon are arranged on a spiral bottle cap of the storage bottle. The sampling and pre-treatment mixing device for the clostridium difficile infected sample is simple in structure; the sample can be conveniently collected and the sample is prevented from being polluted; meanwhile, the pre-treatment of the sample before cultivation can also be carried out. The sampling and pre-treatment mixing device for the clostridium difficile infected sample is convenient to use when an excrement sample is collected or detected; absolute ethyl alcohol is convenient to add; the cultivation positive rate of clostridium difficile is easily improved, the environment is prevented from being polluted and the working difficulty of medical personnel is relieved.

Description

technical field [0001] The invention belongs to the field of medical devices, and in particular relates to a sample pretreatment and mixing device for samples infected by Clostridium difficile. Background technique [0002] Clostridium difficile is a microorganism that can only grow in pure anaerobic culture. The diseases caused by it cause more than tens of thousands of deaths every year in Europe and the United States, and have more than billions of dollars in additional medical costs. At present, the detection of Clostridium difficile has not been popularized in domestic hospitals, mainly because of harsh culture conditions, low positive rate and cumbersome detection methods. The positive rate of Clostridium difficile selective medium directly inoculated after stool sample sampling is low. Studies have found that the positive rate will be greatly increased after the stool sample is mixed with absolute ethanol and then inoculated. [0003] The sampling device currently us...

AI Technical Summary

Problems solved by technology

It is widely used and the price is low, but it has many defects and cannot be well used for sampling and inspection of Clostridium difficile

First, this type of spoon-shaped sampling device can only pick loose and soft stools, but not watery stools. Patients with Clostridium difficile infection often pass watery stools, mucus-like stools, or mucus-bloody stools, especially for bedridden patients. For delirious patients, the hip pad is often used, and the patient's stool is directly discharged on the hip pad, so sampling is more difficult; second, a small amount of stool is enough for routine examination, but for other examinations or scientific research, such as extracting When the DNA of pathogenic microorganisms in stool is used for molecular biological identification of pathogenic bacteria, a large amount of stool is required, so it is more difficult to pick more water samples, and the syringe-type suction device just solves this problem; Third, the stool samples are directly inoculated with Clostridium difficile CCFA selective medium, and the positive rate of culture is not high. The positive rate can be significantly increased after picking the samples and mixing them with absolute ethanol, but there are also two cumbersome steps. First, pick the samples For microcentrifuge tubes, the small tube walls are often contaminated, and it is not easy to pick, which is time-consuming. Secondly, after adding absolute ethanol to the microcentrifuge tube, the specimen will condense into a lump, and a shaker is required to mix

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