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Medicine for treating phthisis

A pulmonary tuberculosis and drug technology, applied in the field of drugs for the treatment of pulmonary tuberculosis, can solve the problems that patients are prone to drug resistance, serious adverse reactions, and affect the treatment effect, and achieve low drug resistance, fewer side effects and adverse reactions, and low treatment costs. Effect

Inactive Publication Date: 2014-07-23
HUZHOU KONCH PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The treatment of this disease generally adopts western medicine, but the adverse reactions of this kind of western medicine are often serious, and some patients are prone to drug resistance, which affects the treatment effect, so it is often necessary to use two or more drugs in combination, and the treatment cost is high

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] 23 parts of white mustard seed, 12 parts of walnut kernel, 4 parts of ginger, 6 parts of ephedra, 8 parts of mint, 2 parts of licorice, 12 parts of Sichuan pepper, 18 parts of clove, 32 parts of sophora flavescens, 15 parts of litsea cubeba, 12 parts of perilla .

[0012] Preparation method: Weigh each raw material by weight, crush it to 60 mesh, add 8 times the volume of 80% ethanol to soak for 10 h, reflux extraction twice, each time for 1 h, filter the alcohol extract, combine, and reduce pressure Concentrate to 50 ? The relative density at C is 1.12, and it is made into tablets with pharmaceutical auxiliary materials after spray drying.

Embodiment 2

[0014] 25 parts of white mustard seed, 10 parts of walnut kernel, 3 parts of paojiang, 7 parts of ephedra, 7 parts of mint, 3 parts of licorice, 13 parts of Sichuan pepper, 20 parts of clove, 30 parts of sophora flavescens, 13 parts of litsea cubeba, 15 parts of perilla .

[0015] Weigh each raw material according to parts by weight, crush it to 70 mesh, add 10 times the volume of 80% ethanol to soak for 10 h, reflux extraction twice, each time for 1 h, filter the alcohol extract, combine, and concentrate under reduced pressure to 55 ? The relative density at C is 1.12, and it is made into tablets with pharmaceutical auxiliary materials after spray drying.

Embodiment 3

[0017] 27 parts of white mustard seed, 8 parts of walnut kernel, 2 parts of ginger, 8 parts of ephedra, 6 parts of mint, 4 parts of licorice, 15 parts of Sichuan pepper, 22 parts of clove, 28 parts of flavescens, 10 parts of litsea cubeba, 17 parts of perilla .

[0018] Weigh each raw material according to parts by weight, crush it to 80 mesh, add 12 times the volume of 80% ethanol to soak for 10 h, reflux extraction twice, each time for 1 h, filter the alcohol extract, combine, and concentrate under reduced pressure to 60 ? The relative density at C is 1.12, and it is made into tablets with pharmaceutical auxiliary materials after spray drying.

[0019] Medicine of the present invention passes through 4 groups of a hospital in Huzhou City, Zhejiang Province, each group of 100 clinical trials (taking the tablet of the present invention according to the required dose every day, 6 months course of treatment), the results are as follows:

[0020] Number of people cur...

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PUM

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Abstract

The invention provides a medicine for treating phthisis. The medicine for treating phthisis is prepared from the following raw materials in parts by weight: 20-30 parts of semen brassicae, 5-15 parts of walnut kernel, 1-5 parts of baked ginger, 5-10 parts of ephedra, 5-10 parts of mint, 1-5 parts of liquorice, 8-20 parts of Sichuan pepper, 15-25 parts of clove, 25-35 parts of radix sophorae flavescentis, 8-20 parts of litsea cubeba and 10-20 parts of purple perilla. The medicine for treating phthisis is remarkable in curative effect on phthisis, few in side effects and adverse effects and not liable to generate medicine tolerance, only needs to be independently administrated, and is low in treatment cost.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, in particular to a medicine for treating pulmonary tuberculosis. Background technique [0002] Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis, which can invade many organs, with pulmonary tuberculosis infection being the most common. The excretor is an important source of infection. After the human body is infected with Mycobacterium tuberculosis, the disease may not necessarily occur. When the resistance is reduced or the cell-mediated allergic reaction is increased, it may cause clinical disease. The treatment of this disease generally adopts western medicine, but the adverse reactions of this kind of western medicine are often serious, and some patients are prone to drug resistance, which affects the treatment effect, so it is often necessary to use two or more drugs in combination, and the treatment cost is high . [0003] Contents of the in...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P31/06
Inventor 王建荣
Owner HUZHOU KONCH PHARMA