A kind of hydrogel dressing and preparation method thereof

Abstract

The invention discloses a hydro-dressing. The hydro-dressing comprises the following components in percentage by mass: 3-5 percent of MPC-VPBA (methacryloyloxyethylphosphorylcholine-vinylphenylboronic acid) copolymer, 2-3 percent of PVA (polyvinyl acetate), 0.01-0.1 percent of antibacterial, 0.05-0.2 percent of conglutinant matter and 91.7-94.94 percent of solvent. The method for preparing the hydro-dressing comprises the following steps: (1) preparing the MPC-VPBA aqueous liquid; (2) preparing a PVA aqueous liquid; (3) filtering the PVA aqueous liquid which is cooled to room temperature through a 5mu m screen, and sequentially adding the antibacterial and the conglutinant matter in the filtered liquid, and uniformly stirring; and (4) mixing: uniformly mixing the liquid prepared in the step (1) and the liquid prepared in the step (3) to form the hydro-dressing. The hydro-dressing has the characteristics of high swelling ratio, good conformality, small irritation to wounds, no adhesion with tissues, and relatively stable and durable drug effect; and the preparation of the hydro-dressing can be completed at room temperature, does not need external crosslinking agent, and is particularly suitable for wild environmental application.

Description

technical field [0001] The invention relates to a medical dressing and a preparation method thereof, in particular to a hydrogel dressing and a preparation method thereof, and belongs to the technical field of medical polymer biomaterials. Background technique [0002] Medical dressings are materials used to cover wounds to achieve the effects of controlling bleeding, preventing infection, absorbing secretions, and promoting rapid wound healing. An ideal medical dressing should have the following characteristics: absorbable exudate, keep the wound clean; the contact surface can maintain a certain humidity, and has a good ventilation effect, accelerating wound healing; can effectively block and kill harmful microorganisms; remove the dressing It is not easy to adhere to the wound. The most commonly used traditional dressing is cotton gauze soaked in medicinal liquid, which is applied on the wound or embedded in the wound to stop bleeding, relieve pain, and reduce inflammatio...

AI Technical Summary

Problems solved by technology

The most commonly used traditional dressing is cotton gauze soaked in medicinal liquid, which is applied on the wound or embedded in the wound to stop bleeding, relieve pain, and reduce inflammation. However, the traditional cotton gauze dressing has many shortcomings: absorption The amount of liquid is small, usually only 4-5 times its own weight, the moisturizing effect is poor, it is easy to cause tissue dehydration, it is easy to adhere to the wound surface, and it is difficult to remove, etc.

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