The invention discloses a high speed steel finishing roll of a wire bar mill and a manufacturing method of the high speed steel finishing roll, belonging to the technical field of machining and casting. The finishing roll consists of a roll neck and a roll body comprising a working layer, a primary core and a core part; the working layer comprises the following chemical components: 1.50-2.50 percent of C, 0.40-1.00 percent of Si, 0.40-0.80 percent of Mn, less than or equal to 0.03 percent of P, less than or equal to 0.03 percent of S, 4.0-8.0 percent of Cr, 0.50-1.00 percent of Ni, 5.00-8.00 percent of Mo and 5.00-8.00 percent of V. In the casting process, the casting temperature and the rotating speed of a centrifuge can be controlled by adopting manners of high-temperature discharge from a furnace, low-temperature casting, high-speed mold filling and slow-down solidification. According to the high speed steel finishing roll and the manufacturing method of the high speed steel finishing roll, the adaptability of high speed steel materials on bar rolling can be effectively solved by reasonable design of alloy components and the processing technology, and the wear resistance and the millimeter rolling quantity of the roll are improved; in addition, the high speed steel finishing roll has favorable thermal crack resistance, and the working efficiency of a heavy and medium plate mill can be greatly improved.