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Production method of HP infection-induced chronic gastritis medicine

A production method and technology for chronic gastritis, applied in the direction of medical formula, drug combination, antibacterial drugs, etc., can solve the problems of poor treatment effect and high cost, achieve the effect of eliminating clinical symptoms, simple and easy method, suitable for clinical application

Inactive Publication Date: 2014-10-01
YANKUANG GRP CO LTD
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AI Technical Summary

Problems solved by technology

[0003] The purpose of this invention is to provide a kind of production method of the medicine for treating chronic gastritis caused by HP infection, the medicine produced solves the defects of poor therapeutic effect and high cost of the original medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0015] Take 10g of Wulingzhi, 10g of Puhuang, 15g of Danshen, 10g of Baiji, 6g of Chuanxiong, 10g of coke betel nut, 10g of black medicine, 6g of sandalwood, 6g of amomum, and add 830ml of water. Pack decocting, add sandalwood and amomum after the medicinal liquid is boiled for 10 minutes, and boil to obtain 150ml of concentrated liquid. After the concentrated solution was filtered and cooled to normal temperature, 220 mg of bismuth potassium citrate, 500 mg of clarithromycin, and 1000 mg of tinidazole were added, and the product was obtained by high-temperature sterilization and vacuum packaging.

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Abstract

A production method of an HP infection-induced chronic gastritis medicine comprises the following steps: taking excrementum pteropi 10 g, pollen typhae 10 g, radix salviae miltiorrhizae 15 g, bletilla 10 g, szechuan lovage rhizome 6 g, scorched betel nut 10 g, radix linderae 10 g, santalwood 6 g and villous amomum 6 g, adding 830 ml of water, decocting to obtain a concentrated solution of 150 ml, filtering, cooling to the ordinary temperature, then adding bismuth potassium citrate 220 mg, clarithromycin 500 mg and tinidazole 1000 mg, adopting high-temperature sterilized vacuum packing to obtain the product. The production method is simple and feasible; the produced medicine is superior to the treatment only adopting Livzon triple in 14C experimental detection scoring when used for treating chronic gastritis, and has a better effect in treating chronic gastritis; therefore, the traditional Chinese and western combined medicine is more suitable for clinical popularization and application.

Description

technical field [0001] The invention relates to a production method of a medicine for treating chronic gastritis caused by HP infection. Background technique [0002] Helicobacter pylori (H. pylori) is a microaerophilic G-bacteria. It was discovered by Marshall and Warren in 1982 on the surface of the gastric mucosa in the submucosal layer of the human digestive tract. Studies have shown that Helicobacter pylori (HP) infection is an important cause of chronic gastritis. At present, the most effective gastric triple or quadruple therapy, the antibiotics clinically used to eradicate H. pylori mainly include nitroimidazoles, large Cyclic lactones, β-lactams, quinolones, etc. Due to the improvement of HP drug resistance and the widespread use of antibiotics, a large number of H. pylori drug-resistant strains have emerged, making it more and more difficult to eradicate H. pylori, causing its eradication rate to drop below 90% again. Rational use of antibiotics can cause advers...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61P1/04A61P31/04
Inventor 崔文海杜庆顺沙海燕
Owner YANKUANG GRP CO LTD
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