Compound ovateleaf holly bark soft capsule and preparation method thereof

Abstract

The invention discloses a method for preparing a compound ovateleaf holly bark soft capsule, and belongs to the technical field of a traditional Chinese medicinal preparation. The method comprises the following steps: extracting rhizoma cyperi volatile oil; preparing a compound ovateleaf holly bark extract: preparing a substrate by the steps of heating vegetable oil, soyabean lecithin and beewax under continuously stirring so as to melt solid substances, keeping on heating for a certain period, keeping on stirring until oil foam completely disappears after heating is stopped, and cooling to obtain the substrate; preparing the content: adding the substrate into the compound ovateleaf holly bark extract, uniformly mixing, grinding by a colloid mill, adding the rhizoma cyperi volatile oil, and uniformly stirring to obtain the content; preparing a glue solution; pressing: preparing the soft capsule by a pressing method. The method is simple in process and avoids loss of effective components; the compound ovateleaf holly bark soft capsule prepared by the method has the characteristics of good sealing performance, stable quality, quick disintegration in storage period, quick curative effect, and high bioavailability.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a compound jiubing soft capsule and a preparation method thereof. Background technique [0002] Compound Jiubing Capsule is a traditional Chinese medicine compound preparation made from three medicinal materials of Jiubing, Dongfengju and Cyperus cyperus. Compound Jiubiying Capsules is recorded in Volume 10 of the Ministry of Health Drug Standards for Traditional Chinese Medicine Prescriptions, and the standard number is WS3-B-1986-95. The preparation method of the compound Jiubingying capsule in this standard is "1000g of Jiubingying, 1000g of Dongfengju, 1000g of Rhizoma Cyperi, extract volatile oil from Rhizoma Cyperi, add the dregs of Jiubingying, Dongfengju, add water and decoct twice, combine the decoction, Filtrate, concentrate the filtrate to an appropriate amount, let it cool, add an equal amount of ethanol, let it stand overnight, filt...

AI Technical Summary

Problems solved by technology

However, when preparing traditional Chinese medicine soft capsules with the above-mentioned traditional methods, problems of layering and agglomeration of the content often occur during the preparation process, resulting in unstable loading and low production efficiency.

More importantly, in the traditional Chinese medicine soft capsule prepared by the above-mentioned traditional method, the contents tend to adhere to the capsule shell during storage, resulting in the problem that the disintegration time limit of the Chinese medicine soft capsule will fail in a short period of time.

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