Unlock instant, AI-driven research and patent intelligence for your innovation.

Preparation method of electrochemical sensor based on graphene film modified electrode

A graphene film, electrochemical technology, applied in the direction of material electrochemical variables, etc., can solve the problems of poor control of film thickness, introduction of toxic chemicals, etc., and achieve the effect of high sensitivity

Inactive Publication Date: 2014-11-05
WUXI BAILING SENSING TECH
View PDF6 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The deposition method of graphene on the electrode surface is very important for electrosensing and electrocatalysis applications, but the graphene film modified electrode prepared by chemical reduction of graphene oxide sheets has some inherent defects, such as poor control of film thickness, would introduce toxic chemicals, etc.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0011] In order to deepen the understanding of the present invention, the present invention will be further described below in conjunction with implementation.

[0012] A method for preparing an electrochemical sensor based on an electroreduced graphene oxide film modified glassy carbon electrode for sibutramine detection, the steps are as follows:

[0013] (1) Preparation of graphene oxide: 4g of graphite powder was added to 180mL of concentrated sulfuric acid at 0°C, 32g of potassium permanganate was added under stirring in an ice-water bath, the mixture was stirred at 75°C for 3h and then used at 50°C Dilute with 800mL of water, add 50mL of 30% hydrogen peroxide dropwise, wash with 100mL of 1:10 hydrochloric acid solution after filtration, and then wash with water until the pH of the solution reaches 6.3. The obtained yellow solid is vacuum dried at 60°C for 15 hours and ground into powder.

[0014] (2) Preparation of electrochemically reduced graphene oxide modified glassy...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

According to the invention, an electrochemical sensor based on an electro reduction oxidation graphene film modified glass carbon electrode is prepared and is used for detecting a medicament sibutramine (SHM) for the treatment of obesity. The invention employs a drop coating and electrochemical reduction method, and uses oxidation graphene for modification on glass carbon electrode, so as to prepare a novel electrochemical sensor. The electrochemical sensor involved in the invention shows the characteristics of simpleness, rapidness and high sensitivity in the detection process of SHM in pure samples and biological samples, and can be successfully used for the detection of SHM in human plasma and urine.

Description

technical field [0001] The invention relates to the preparation of an electrochemical sensor, in particular to a preparation method of a modified glassy carbon electrode based on an electroreduced graphene oxide film. Background technique [0002] Sibutramine hydrochloride (SHM), the chemical name is N-{1-[1-(4-chlorophenyl)-epoxybutyl]-3-methylbutyl}-N,N-dimethylamine hydrochloride Monohydrate, an agent used in the treatment of obesity. [0003] Quantitative detection of SHM in humans and pharmaceutical preparations generally uses spectrophotometry, high performance liquid chromatography, and flow injection methods. These methods usually have disadvantages such as long analysis time, complicated sampling or purification process, and online extraction of samples. Recently, a suspended mercury drop electrode has been reported in the literature for the detection of SHM in beverages and pharmaceutical preparations by voltammetry, but this method involves the use of mercury ele...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): G01N27/26G01N27/30
Inventor 孙京华潘正海
Owner WUXI BAILING SENSING TECH