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Unmarked guided-mode resonance Brewster sensor detection device

A technology of guided mode resonance and detection device, which is applied in the measurement of phase influence characteristics, etc., can solve the problems of small movement and the detection sensitivity of the sensor does not meet the required requirements, and achieves the effect of high integration and improved sensitivity.

Inactive Publication Date: 2014-11-26
YANGTZE DELTA REGION INST OF TSINGHUA UNIV ZHEJIANG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In actual use, due to the very small shift of the resonant wavelength of the biological sample to be measured, usually on the order of nanometers, the detection sensitivity of the sensor cannot meet the required requirements.

Method used

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  • Unmarked guided-mode resonance Brewster sensor detection device
  • Unmarked guided-mode resonance Brewster sensor detection device
  • Unmarked guided-mode resonance Brewster sensor detection device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] 1) Turn on the switch of the incident light source component, the guided mode resonant grating sensor and the detection optical component; 2) The laser light source 1 generates the incident light, which is obliquely incident on the grating layer 5 of the guided mode resonant grating sensor through the beam expander group 2, and then passes through Guided mode resonance is generated after the waveguide layer 6 and the substrate 7; 3) The air with a refractive index of 1 is closely combined with the guided mode resonant grating sensor, and the CCD line array 3 detects the laser signal at a resonance angle position of 44.68°.

Embodiment 2

[0021] 1) Turn on the switch of the incident light source component, the guided mode resonant grating sensor and the detection optical component; 2) The laser light source 1 generates the incident light, which is obliquely incident on the grating layer 5 of the guided mode resonant grating sensor through the beam expander group 2, and then passes through Guided mode resonance is generated after the waveguide layer 6 and the substrate 7; 3) The water with a refractive index of 1.333 is closely combined with the guided mode resonant grating sensor, and the CCD line array 3 detects the laser signal at a resonance angle position of 30.22°.

Embodiment 3

[0023] 1) Turn on the switch of the incident light source component, the guided mode resonant grating sensor and the detection optical component; 2) The laser light source 1 generates the incident light, which is obliquely incident on the grating layer 5 of the guided mode resonant grating sensor through the beam expander group 2, and then passes through Guided mode resonance is generated after the waveguide layer 6 and the substrate 7; 3) Isopropanol with a refractive index of 1.377 is closely combined with the guided mode resonant grating sensor, and the CCD linear array 3 detects the resonance angle position of the laser signal at 28.63°.

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Abstract

The invention discloses an unmarked guided-mode resonance Brewster sensor detection device. The unmarked guided-mode resonance Brewster sensor detection device comprises an incident light source assembly, a guided-mode resonance grating sensor and a detection optical assembly, wherein the incident light source assembly comprises a laser light source and a beam expander group; the guided-mode resonance grating sensor comprises a grating layer, a waveguide layer and a substrate; the detection optical assembly comprises a CCD linear array and a drive circuit thereof; the beam expander group is installed in front of the laser light source, the waveguide layer is installed above the substrate, the grating layer is installed above the waveguide layer, and the CCD linear array is installed right above the grating layer. The unmarked guided-mode resonance Brewster sensor detection device is high in integration degree and suitable for detecting high-flux samples; the design for entering a guided-mode resonance optical device at a Brewster angle is favorable for actually establishing a biochemical detection device and improving the unmarked optical detection sensitivity.

Description

technical field [0001] The invention relates to an optical detection device, in particular to a marker-free guided mode resonance Brewster sensor detection device. Background technique [0002] Label-free optical detection is a new type of detection technology for direct measurement of biochemical reactions established by using phenomena such as coherent reflection (coherent reflection), diffraction (Diffractive Optics) and surface plasmon resonance (Surface Plasmon Resonance, SPR). This technology avoids marking and destroying the object to be detected, and eliminates the possibility of markers interfering with the detection. It is especially suitable for the interaction process between biomolecules and the application detection that requires extremely low concentrations. It is used in the fields of environmental and food safety monitoring. It has broad application prospects. [0003] Optical biosensors based on Guided-mode Resonance (GMR) have excellent optical sensitivit...

Claims

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Application Information

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IPC IPC(8): G01N21/41
Inventor 王振华蔡强陈强俞锡鹏梁伟陈诚
Owner YANGTZE DELTA REGION INST OF TSINGHUA UNIV ZHEJIANG
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