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Application of disodium adenosine triphosphate in preparation of drug for treating diabetic foot

A kind of technology of adenosine triphosphate disodium and adenosine triphosphate disodium tablets, applied in the field of chemical medicine

Inactive Publication Date: 2014-12-03
陈钏黄
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, due to peripheral circulatory disturbance, high blood viscosity, tissue hypoxia, reduced compensatory repair ability, difficult wound healing, and more prone to concurrent infection
[0006] Diabetic foot treatment includes drug therapy, interventional therapy, and stem cell transplantation. Traditional endocrinology treatment of diabetic foot is mainly to control multiple risk factors such as blood sugar, blood pressure, and blood lipids. On the basis of activating blood circulation, removing blood stasis, and vasodilating drugs to improve local microcirculatory disturbance, but in severe cases, it is mostly caused by occlusion of large vessels, and the effect of simple drug treatment is not good. Interventional therapy can significantly improve the lower extremity of these patients. Vascular disease, improve quality of life

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Example 1: Clinical research on treating diabetic foot with adenosine triphosphate disodium

[0023] In this study, on the basis of intensive insulin control of blood sugar, local debridement of skin ulcers, anti-infection and nerve nutrition, combined with adenosine triphosphate disodium in the treatment of diabetic foot, the clinical efficacy was observed.

[0024] 1 Materials and methods

[0025] 1.1 General information

[0026] 44 cases of inpatients with diabetic foot in the Department of Orthopedics of Fuzhou First People's Hospital were selected. All patients met the World Health Organization's diagnostic criteria for diabetes (Qian Rongli. New Diagnosis and Types of Diabetes [J]. Chinese Journal of Diabetes, 2000.8 (1): 5-6). The diagnosis of diabetic foot conforms to the diagnostic criteria issued by the International Diabetic Foot Working Group / IDF Advisory Group (International Diabetic Foot Working Group / IDF Advisory Group. 2007 Practical Guidelines...

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PUM

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Abstract

The invention belongs to the field of chemicals, relates to a novel pharmaceutical purpose of drugs, and particularly relates to an application of a disodium adenosine triphosphate drug in preparation of a drug for treating a diabetic foot. The invention discloses an application of disodium adenosine triphosphate in preparation of a drug for treating a diabetic foot. The disodium adenosine triphosphate medicine is disodium adenosine triphosphate for injection, a disodium adenosine triphosphate injection, or a disodium adenosine triphosphate tablet, or disodium adenosine triphosphate magnesium chloride or a disodium adenosine triphosphate-magnesium chloride injection or a disodium adenosine triphosphate enteric capsule.

Description

[0001] Technical field: [0002] The invention belongs to the field of chemical medicines and relates to a new pharmaceutical application of medicines, in particular to the application of adenosine triphosphate disodium in the preparation of medicines for treating diabetic foot. [0003] Background technique: [0004] Diabetic foot (Diabetic Foot, DF) is a general term for foot pain, deep skin ulcers, extremity gangrene and other lesions caused by comprehensive factors of diabetes. and deep tissue damage. Under the influence of high blood sugar for a long time, the blood vessels in the lower limbs of diabetic patients will harden, the blood vessel walls will thicken, and the elasticity of blood vessels will decrease, and the blood vessels will be prone to thrombus, which will lead to the occlusion of blood vessels in the lower limbs, and the damage of peripheral nerves, which will lead to tissue lesions in the lower limbs. The foot is prone to edema, rot, necrosis and s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7076A61P3/10A61P9/14A61P17/02A61P9/12
Inventor 陈钏黄
Owner 陈钏黄
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