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Electrode, device and method for deep brain stimulation

A technology that stimulates electrodes and deep brain, applied in the direction of internal electrodes, head electrodes, electrodes, etc., can solve the problems of psychological dependence, inability to effectively prevent relapse, etc., and achieve the effect of expanding the scope of action

Active Publication Date: 2016-06-08
SCENERAY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the existing treatment methods at home and abroad have good detoxification effects, but they are powerless against the psychological dependence caused by drugs, and cannot effectively prevent relapse, resulting in a relapse rate as high as 97% within six months, and patients often fall into the "drug use-detoxification" - vicious circle of relapse

Method used

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  • Electrode, device and method for deep brain stimulation
  • Electrode, device and method for deep brain stimulation
  • Electrode, device and method for deep brain stimulation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] The distance P1 between the output electrode contacts 810 and 820 in the first group of output electrode contacts is 0.5mm.

[0049] The distance P2 between the first group of output electrode contacts and the second group of output electrode contacts is 3.5mm.

[0050] The distance P3 between the output electrode contacts 930 and 940 in the second group of output electrode contacts is 0.5mm.

[0051] The lengths L1, L2, L3, and L4 of the electrode contacts 810, 820, 930, and 940 are all 0.5 mm.

Embodiment 2

[0053] The distance P1 between adjacent electrode contacts 810 and 820 in the electrode contact group of the first intracerebral functional area is 2mm.

[0054] The distance P2 between the electrode contact group of the first functional area of ​​the brain and the electrode contact group of the second functional area of ​​the brain is 4 mm.

[0055] The distance P3 between the output electrode contacts 930 and 940 in the second set of output electrode contacts is 4 mm.

[0056] The lengths L1, L2, L3, and L4 of the electrode contacts 810, 820, 930, and 940 are all 3 mm.

Embodiment 3

[0058] Typical case: male, 38 years old, married, height 180cm, weight 60kg. Repeated use of heroin for 16 years, in the form of scalding and smoking, with a dose of 0.5g / day. There is a sense of euphoria when using it, and discomfort symptoms such as irritability, tearing, yawning, muscle aches, insomnia, etc. after withdrawal, and a strong sense of psychological desire. He has had compulsory withdrawal and self-abstinence for 10 times, and the longest withdrawal time is 18 months (working in other places, when he is about to arrive at his hometown by train, he will have a strong psychological desire, and he will recover on the day he returns to his hometown. Suck). When living locally, the longest withdrawal time is 6 months. During the period of drug use, he can maintain his work intermittently (in order to raise drug funds), only interested in drug use, and indifferent to other things. Although married, the frequency of sexual life between husband and wife is low, about...

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Abstract

The invention discloses a deep brain stimulation electrode, which includes at least two sets of output electrode contacts, and at least one output electrode contact is provided in each set of output electrode contacts. At least one output electrode contact of the first set of output electrode contacts is located in the nucleus accumbens of the brain after the installation is completed; at least one output electrode contact of the second set of output electrode contacts is located in the brain after the installation is completed The forelimb part of the internal capsule. The invention also discloses a deep brain stimulation device with the electrode and a deep brain stimulation method for drug addiction treatment. The present invention realizes simultaneous simultaneous stimulation of dual functional areas of the nucleus accumbens and internal capsule forelimb with one electrode, and can apply targeted stimulation to different functional areas of the brain, improving the effectiveness of deep brain electrical stimulation in getting rid of drug addiction and obsessive-compulsive disorder , efficacy and safety in the treatment of psychiatric disorders such as depression.

Description

technical field [0001] The invention belongs to the technical field of implantable medical devices, and in particular relates to an electrode, device and method for deep brain stimulation. Background technique [0002] The reward circuit of the mesolimbic-cortical system is closely related to addictive behavior, depression and obsessive-compulsive disorder. [0003] Take drug addiction as an example: drug abuse and dependence are important social problems facing the world. The 2014 China Drug Rehabilitation Report shows that by the end of 2013, there were a total of 2.475 million registered drug addicts across the country, of which 1.358 million were opioid drug abusers, accounting for 54.9%; in 2013, there were more than 365,000 newly registered drug addicts nationwide; The ratio of the number of people to the number of registered drug users is 10:1. Therefore, the actual number of drug users is much higher than the current registered number, and there is a high demand for...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61N1/05A61N1/36
CPCA61N1/0534
Inventor 豆美娟
Owner SCENERAY