Thermosensitive copolymer as well as synthesis method and hydrogel system of thermosensitive copolymer
A synthesis method and copolymer technology, applied in the field of temperature-sensitive copolymers and their synthesis, and hydrogel systems, can solve the problems of poor reversibility of polypeptide temperature-sensitive hydrogels, and achieve fixed-point release and good reversible heat The effect of changing performance and not easy to wander
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0034] A temperature-sensitive copolymer is a polyethylene glycol-poly(propylene glycol) composed of poly(alanine-valine) as a hydrophobic segment and monomethyl ether polyethylene glycol as a hydrophilic segment. amino acid-valine) block copolymer, wherein the content of alanine in the hydrophobic segment poly(alanine-valine) is 23.5wt%, and the content of valine is 76.5wt%.
[0035] Further, the content of monomethyl ether polyethylene glycol in the hydrophilic segment in the copolymer is 52.5 wt%, and the content of poly(alanine-valine) in the hydrophobic segment is 47.5 wt%.
[0036] The number average molecular weight of the monomethyl ether polyethylene glycol of the hydrophilic segment described in this example is 1000.
[0037] Further, the number average molecular weight of the monomethyl ether polyethylene glycol of the hydrophilic segment can also be 500, 2000, 3000, 4000 or 5000.
[0038] The synthetic method of the thermosensitive copolymer of the present embodim...
Embodiment 2
[0053] A temperature-sensitive copolymer is a polyethylene glycol-poly(propylene glycol) composed of poly(alanine-valine) as a hydrophobic segment and monomethyl ether polyethylene glycol as a hydrophilic segment. amino acid-valine) block copolymer, wherein the content of alanine in the hydrophobic segment poly(alanine-valine) is 15.2wt%, and the content of valine is 84.8wt%.
[0054] Further, the content of monomethyl ether polyethylene glycol in the hydrophilic segment in the copolymer is 45.0 wt%, and the content of poly(alanine-valine) in the hydrophobic segment is 55.0 wt%.
[0055] Further, the number average molecular weight of the monomethyl ether polyethylene glycol of the hydrophilic segment is 1500.
[0056] The synthesis method of the temperature-sensitive copolymer of this embodiment is the same as that of Embodiment 1.
[0057] The temperature-sensitive hydrogel system of this embodiment is prepared from a temperature-sensitive copolymer, and the concentration o...
Embodiment 3
[0059] A temperature-sensitive copolymer is a polyethylene glycol-poly(propylene glycol) composed of poly(alanine-valine) as a hydrophobic segment and monomethyl ether polyethylene glycol as a hydrophilic segment. Amino acid-valine) block copolymer, wherein, the content of alanine in the hydrophobic segment poly(alanine-valine) is 19wt%, and the content of valine is 81wt%.
[0060] Further, the content of monomethyl ether polyethylene glycol in the hydrophilic segment in the copolymer is 55.0 wt%, and the content of poly(alanine-valine) in the hydrophobic segment is 45.0 wt%.
[0061] Further, the number average molecular weight of the monomethyl ether polyethylene glycol of the hydrophilic segment is 5000.
[0062] The synthesis method of the temperature-sensitive copolymer of this embodiment is the same as that of Embodiment 1.
[0063] The temperature-sensitive hydrogel system of this embodiment is prepared from a temperature-sensitive copolymer, and the concentration of t...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com