Multi-concentration animal oral-nasal inhalation dynamic exposure equipment

A multi-concentration, oral-nose technology, applied in the preparation of test samples, measuring devices, instruments, etc., can solve the problems of inhalation toxicology experiments of animals, improve the degree of automation and control accuracy, save usage, and prevent poisonous gas. leaked effect

Active Publication Date: 2015-02-25
BEIJING HUIRONGHE TECH
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  • Abstract
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  • Claims
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Problems solved by technology

[0004] The purpose of the embodiments of the present invention is to provide a multi-concentration animal oral and nasal inhalation dynamic exposure equipment, which solves th

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  • Multi-concentration animal oral-nasal inhalation dynamic exposure equipment
  • Multi-concentration animal oral-nasal inhalation dynamic exposure equipment
  • Multi-concentration animal oral-nasal inhalation dynamic exposure equipment

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Example Embodiment

[0035] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the specific embodiments will be described in detail below in conjunction with the accompanying drawings.

[0036] Such as figure 1 with figure 2 As shown, the multi-concentration animal oral and nose inhalation dynamic exposure device includes an air compressor 111 for providing compressed air, an aerosol generation system 1, an oral and nose exposure unit 6, and an exhaust gas recovery processing system 9; at the outlet of the air compressor 111 An air flow control valve 19 is provided at the place; the oral and nose exposure unit 6 includes an experimental group exposure chamber 63 and an experimental animal holder 62; the aerosol generation system 1 includes an aerosol generator 11 for controlling the air in the aerosol generator 11 The first air flow controller 17 for the intake air volume, the liquid medicine bottle 13 for supplying the liquid medicine to ...

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Abstract

The invention discloses a multi-concentration animal oral-nasal inhalation dynamic exposure equipment which comprises an air compressor, an aerosol generation system, an oral-nasal exposure unit and a waste gas recovery treatment system, wherein the oral-nasal exposure unit comprises an experiment group exposure chamber; the aerosol generation system is connected with an aerosol inlet of the experiment group exposure chamber; a waste gas outlet of the experiment group exposure chamber is connected with the waste gas recovery treatment system; the equipment also comprises a multi-concentration dilution system; the experiment group exposure chamber comprises multiple sections of experiment exposure chambers; and the multi-concentration dilution system comprises a second aerosol diluter arranged among the sections of experiment exposure chambers and a third air flow controller for controlling the air inflow in the second aerosol diluter. The second aerosol diluter is arranged among the sections of experiment exposure chambers and used for diluting the aerosol entering the second section of experiment exposure chamber from the first section of experiment exposure chamber so as to meet the experiment requirements and perform experiment comparison in different concentration conditions.

Description

technical field [0001] The invention relates to the field of animal inhalation toxicology experiments, in particular to a multi-concentration animal oral and nasal inhalation dynamic exposure device. It can be used for the safety evaluation of inhalation toxicology drugs, the inhalation experiment research of acute toxicity of pesticides, the construction of various animal models of COPD and the experimental research of its drug efficacy, the research of the influence of air pollutants on the respiratory system of animals, etc. Background technique [0002] At present, in various scientific researches related to inhalation toxicology, especially the research on some substances harmful to human health, such as PM2.5, etc., because it cannot be tested directly or first on humans, experimental animals are often used for inhalation. exposure evaluation. Therefore, animal exposure devices have a wide range of applications in industry, agriculture, medicine, environmental polluti...

Claims

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Application Information

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IPC IPC(8): G01N35/00G01N1/38G01N33/00
Inventor 张俊杰鹿建春刘玉杰郑劲林
Owner BEIJING HUIRONGHE TECH
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