Supercharge Your Innovation With Domain-Expert AI Agents!

A kind of application of apigenin-7-o-β-d-glucuronide

A technology of glucuronide and apigenin, which is applied in the application field of flavonoid glycosides, and can solve the problems that there is no function of apigenin-7-o-β-D-glucuronide

Active Publication Date: 2019-03-05
HEBEI YILING MEDICINE INST
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] There is currently no information on the role of apigenin-7-o-β-D-glucuronide in inhibiting thrombosis

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of application of apigenin-7-o-β-d-glucuronide
  • A kind of application of apigenin-7-o-β-d-glucuronide
  • A kind of application of apigenin-7-o-β-d-glucuronide

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0126] Embodiment 1: tablet preparation

[0127] Weigh 30g of apigenin-7-o-β-D-glucuronide, add 100g of microcrystalline cellulose, 200g of lactose, mix well, add croscarmellose sodium, mix well, and use a 24-mesh sieve Granulate, dry at 70°C, granulate, add 1% magnesium stearate, mix well, compress into tablets, and make 1000 tablets.

Embodiment 2

[0128] Embodiment 2: capsule preparation

[0129] Weigh 12g of apigenin-7-o-β-D-glucuronide, add 50g of microcrystalline cellulose, add 10g of crospovidone, 130g of lactose, mix well, add 30ml of 5% povidone K30 aqueous solution , add 15ml of water, fully stir, mix well, granulate with 24 mesh sieve, dry at 70°C, granulate, add 1% magnesium stearate, mix well, pack into capsules to get 1000 capsules.

Embodiment 3

[0130] Embodiment 3: Granule preparation

[0131] Weigh 30g apigenin-7-o-β-D-glucuronide, add 500g sucrose, 2500g dextrin, mix well, add 180ml water, stir well, mix well, granulate with 24 mesh sieve, bake at 70℃ Dried, whole, divided into 500 bags.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an application of apigenin-7-o-β-D-glucuronide, which belongs to the field of medicine application. Apigenin-7-o-β-D-glucuronide is used in the preparation of inhibiting arteries and veins The application of thrombus formation drugs can inhibit the formation of thrombus to a certain extent.

Description

technical field [0001] The invention belongs to the field of medicine application, and in particular relates to the application of flavonoid glycosides. Background technique [0002] The process of blood coagulation or certain formed components in blood sticking to each other to form a solid mass is called thrombosis (thrombosis), and the solid mass formed in this process is called thrombus (thrombus). A thrombus consists of insoluble fibrin, deposited platelets, accumulated white blood cells, and trapped red blood cells. Thrombus is divided into: white thrombus, mixed thrombus, red thrombus and transparent thrombus. [0003] Under physiological conditions, coagulation factors in the blood are continuously activated to produce thrombin, forming a small amount of fibrin, which settles on the intima of the blood vessel, but these small amounts of fibrin are continuously released by the activated fibrinolytic system. Dissolved and activated coagulation factors are continuousl...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7048A61P7/02
CPCA61K31/7048
Inventor 姜新刚贾继明张秋艳赵韶华马艳玲高贤
Owner HEBEI YILING MEDICINE INST
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com