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Water-soluble gel for treating diabetic foot

A technology of water-soluble gel and diabetic foot, which can be used in metabolic diseases, skin diseases, cardiovascular system diseases, etc., and can solve problems such as application and research

Inactive Publication Date: 2015-04-01
河北柯瑞生物医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chinese patent ZL 201010176321.9 discloses a method for extracting active collagen (type I) from donkey hide, but no research has been conducted on its application

Method used

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  • Water-soluble gel for treating diabetic foot
  • Water-soluble gel for treating diabetic foot
  • Water-soluble gel for treating diabetic foot

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Get the biological low antigenicity active collagen (type Ⅰ) stock solution and dilute it with deionized water to obtain a dilution solution with a concentration of 0.3% biological low antigenicity active collagen (type Ⅰ), weigh 95g dilution and 4g glycerin, 0.15g nitric acid Methylparaben and 0.05g of propylparaben were stirred and mixed, then filtered, and then 0.6g of water-soluble silicone oil was added and stirred evenly.

Embodiment 2

[0034] Get the biological low antigenicity active collagen (type Ⅰ) stock solution and dilute it with deionized water to obtain a dilution with a concentration of 0.5% biological low antigenicity active collagen (type Ⅰ), weigh 90g dilution and 4.5g glycerol, 0.25g Methylparaben and 0.15g of propylparaben were stirred and mixed, then filtered, and then 0.5g of water-soluble silicone oil was added and stirred evenly.

Embodiment 3

[0036] Get the biological low antigenicity active collagen (type Ⅰ) stock solution and dilute it with deionized water to obtain a dilution with a concentration of 0.4% biological low antigenicity active collagen (type Ⅰ), weigh 94g dilution and 4.0g glycerol, 0.15g Methylparaben and 0.05g of propylparaben were stirred and mixed, then filtered, and then 0.55g of water-soluble silicone oil was added and stirred evenly.

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PUM

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Abstract

The invention discloses water-soluble gel for treating diabetic foot. The water-soluble gel comprises the following components in parts by weight: 90-95 parts of a biological collagen (type I) diluent with low antigenic activity, 3-5 parts of a moisturizing agent, 0.1-1 part of a bactericide and 0.1-1 part of auxiliary materials. The water-soluble gel disclosed by the invention has biological information of natural macromolecular active collagen (type I) and can induce the regeneration and repair of micro-nerves and micro-vessels of organism tissues, so that the aim of organism restoration is achieved.

Description

technical field [0001] The invention relates to a water-soluble gel for treating diabetic foot, which belongs to the field of natural biological macromolecular medicine. technical background [0002] Diabetic foot is a general term for foot itching, skin ulcers, extremity gangrene and other lesions caused by diabetes. It is foot infection, ulcer and deep tissue destruction related to nerve abnormalities in the lower extremities and peripheral vascular lesions in varying degrees (according to WHO definition). It is a serious complication of diabetic patients, which seriously affects the quality of life of patients. The pathogenesis of diabetic foot is complex, which is different from that of general tissue wounds. Under high sugar concentration, tissue healing is relatively difficult, and neuropathy, loss of neurotrophic effect , Perivascular lesions, local circulation restriction, more unfavorable for wound healing. [0003] Current treatments generally include control of ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/39A61K9/06A61P17/02A61P9/14A61P3/10
CPCA61K38/39
Inventor 奚廷斐杨信诚赵晓峰雷小林
Owner 河北柯瑞生物医药有限公司
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