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Medicine quality detection method for Chenxiang Lubailu tablets

A drug quality and detection method technology, applied in the direction of measuring devices, instruments, scientific instruments, etc., can solve the problems of non-specificity, difficult product quality, and ineffective control of internal quality, etc., to achieve strong specificity, good separation effect, The effect of easy operation

Inactive Publication Date: 2015-04-01
昆明振华制药厂有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The current quality standard of Chenxianglu Bailu Tablets is the national standard promulgated by the State Drug Administration in 1993, and the standard number is: WS 3 -B-1553-93, this method only detects the character, identification, content and other routine items of the tablet, but in the identification, it only conducts qualitative and quantitative research on its bismuth salt and magnesium salt, which is not effective Control its internal quality. This standard method has no specificity, and it is difficult to accurately reflect the quality of the product. It can no longer meet the technical requirements of the modernization of traditional Chinese medicine and the requirements of stable and controllable product quality.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Commercially available Chenxianglu Bailu Tablets, functions and indications: invigorating the stomach, regulating qi and relieving pain. For gastric ulcer, erosive gastritis, hyperacidity, acute and chronic gastritis, gastrointestinal neurosis and duodenitis, etc. Usage and dosage: Take orally, 3 to 5 tablets each time, 3 times a day.

[0031] Specifications: Each tablet weighs 0.5g (containing 0.110g of bismuth subnitrate).

[0032] According to the standard WS for the above-mentioned Chenxianglu Bailu tablets 3 -B-1553-93 conducts detection, including the detection of licorice, tangerine peel, and sichuan wood. The specific operations are as follows:

[0033] 1. Detection of licorice:

[0034] (1) Take the Chenxianglu Bailu tablet to be tested and grind it to 30-40 meshes, weigh 5g precisely, add 40ml of ether, heat and reflux for 1 hour, filter, add 30ml of methanol to the dregs, heat and reflux for 1 hour, filter, and the filtrate is evaporated Dry to obtain the...

Embodiment 2

[0048] Commercially available Chenxianglu Bailu Tablets, functions and indications: invigorating the stomach, regulating qi and relieving pain. For gastric ulcer, erosive gastritis, hyperacidity, acute and chronic gastritis, gastrointestinal neurosis and duodenitis, etc. Usage and dosage: Take orally, 5-8 tablets at a time, 3 times a day.

[0049] Specifications: Each tablet weighs 0.3g (containing 0.060g of bismuth subnitrate).

[0050] According to the standard WS for the above-mentioned Chenxianglu Bailu tablets 3 -B-1553-93 conducts detection, including the detection of licorice, tangerine peel, and sichuan wood. The specific operations are as follows:

[0051] 1. Detection of licorice:

[0052] (1) Take the Chenxianglu Bailu tablet to be tested and grind it to 30-40 meshes, weigh 5g precisely, add 40ml of ether, heat and reflux for 1 hour, filter, add 30ml of methanol to the dregs, heat and reflux for 1 hour, filter, and the filtrate is evaporated Dry to obtain the re...

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PUM

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Abstract

The invention provides a medicine quality detection method for Chenxiang Lubailu tablets. The medicine quality detection method for Chenxiang Lubailu tablets is used for detecting the Chenxiang Lubailu tablets according to standard and further comprises detection for liquorice, dried tangerine peel and common vladimiria roots. The liquorice, the dried tangerine peel and the common vladimiria roots suck a test sample solution, a contrast medicinal solution and a reference solution respectively to perform developing comparison according to thin-layer chromatography. With the adoption of the method, inner quality of Chenxiang Lubailu can be effectively controlled, the product quality can be accurately reflected through detection matched with the existing standard, and the method meets technical requirements of modern development of Chinese traditional medicine and requirements for controllability of stable product quality; according to the method, the liquorice, the dried tangerine peel and the common vladimiria roots contained in the Chenxiang Lubailu tablets are identified and detected with the thin-layer chromatography; and the method has the technical characteristics of simplicity and convenience in operation, good separation effect, high specificity and the like.

Description

technical field [0001] The invention relates to the technical field of drug testing, in particular to a drug quality testing method for Chenxianglu Bailu tablets. Background technique [0002] Chenxianglu Bailu Tablets is a drug approved by the State Food and Drug Administration. It is a plain tablet prepared from the compatibility of licorice, bismuth subnitrate, tangerine peel, magnesium carbonate, Kawasaki, magnesium oxide, rhubarb, sodium bicarbonate, and Shichangpu. , has the effect of invigorating the stomach, regulating qi and relieving pain. For gastric ulcer, erosive gastritis, hyperacidity, acute and chronic gastritis, gastrointestinal neurosis and tenodenitis, etc. [0003] The current quality standard of Chenxianglu Bailu Tablets is the national standard promulgated by the State Drug Administration in 1993, and the standard number is: WS 3 -B-1553-93, this method only detects the character, identification, content and other routine items of the tablet, but in t...

Claims

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Application Information

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IPC IPC(8): G01N30/90
Inventor 李俊何耀莹杨丽芬
Owner 昆明振华制药厂有限公司