Gel preparation for treating cervicitis and cervical erosion and preparation method thereof
A cervical erosion and gel technology, which is applied in the field of medicine, can solve the problems of adverse reactions, easy occurrence, and large differences in the content of active ingredients, and achieves the effects of exact curative effect, rapid effect, and stable drug properties.
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Embodiment 1
[0042] 120g total extract of Sophora flavescens, which contains 18.2g matrine and 18.6g sophoridine;
[0043] 40g total catechin extract, which contains 20.3g catechin and 1.6g epicatechin;
[0044] Hypromellose 8g;
[0045] Glycerin 100g;
[0046] 500g of water;
[0047] 1.5mol / L hydrochloric acid 192ml;
[0048] The gel of this embodiment is prepared like this:
[0049] A, measure the content of matrine and sophoridine in the total extract of Sophora flavescens, calculate the total extract of Sophora flavescens and prepare the materials;
[0050] B, measure the content of catechin and epicatechin in the total extract of catechu, calculate the feeding amount of the total extract of catechu, and prepare materials;
[0051] C, adding water to glycerin is adjusted to be 40% glycerol aqueous solution by volume percentage, for subsequent use;
[0052] D. Dissolve the total extract of Sophora flavescens with 150ml of 1.5mol / L hydrochloric acid solution, add polymer adhesive m...
Embodiment 2
[0056] 220g total extract of Sophora flavescens, which contains 65.6g matrine and 66.3g sophoridine;
[0057] 90g total catechin extract, which contains 65.3g catechin and 8.6g epicatechin;
[0058] Sodium carboxymethyl cellulose 15g;
[0059] Glycerin 200g;
[0060] 200g of water;
[0061] 0.9mol / L hydrochloric acid 400ml;
[0062] The gel of this embodiment is prepared like this:
[0063] A, measure the content of matrine and sophoridine in the total extract of Sophora flavescens, calculate the total extract of Sophora flavescens and prepare the materials;
[0064] B, measure the content of catechin and epicatechin in the total extract of catechu, calculate the feeding amount of the total extract of catechu, and prepare materials;
[0065] C, adding water to glycerin is adjusted to be 60% glycerol aqueous solution by volume percentage, for subsequent use;
[0066] D. Dissolve the total extract of Sophora flavescens with 300 ml of 0.9mol / L hydrochloric acid solution, ad...
Embodiment 3
[0070] The total extract of Sophora flavescens is 133g, which contains 41.1g of matrine and 45.2g of sophoridine;
[0071] 67g total catechin extract, which contains 40.6g catechin and 3.6g epicatechin;
[0072] Hypromellose 12g
[0073] Glycerin 130g
[0074] water 300g
[0075] 0.7mol / L sulfuric acid 200ml;
[0076] The gel of this embodiment is prepared like this:
[0077] A, measure the content of matrine and sophoridine in the total extract of Sophora flavescens, calculate the total extract of Sophora flavescens and prepare the materials;
[0078] B, measure the content of catechin and epicatechin in the total extract of catechu, calculate the feeding amount of the total extract of catechu, and prepare materials;
[0079] C, glycerin is added water and is modulated into the glycerol aqueous solution that volume percentage is 50%, for subsequent use;
[0080] D. Dissolve the total extract of Sophora flavescens with 160ml of 0.7mol / L sulfuric acid solution, add polyme...
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