Method for manufacturing immediately implanted tooth with periodontal bioactivity

A bioactive, manufacturing method technology, applied in the fields of dental implants, dentistry, dental restorations, etc., can solve problems such as gaps, achieve the effects of improving the success rate, shortening the restoration time of missing teeth, and improving the guiding activity of bone tissue

Active Publication Date: 2015-04-22
FOURTH MILITARY MEDICAL UNIVERSITY
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

However, these growth factors are macromolecular proteins, and there are many problems in acquisition, synthesis, localization, delivery, and activity control, especially on the surface of titanium metal implants, how to load organic biomolecules, how to stably maintain their biological activity, and how to To ensure its biological safety, there are still many technical bottlenecks, and there is still a big gap from the actual clinical application conditions of dental implants

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  • Method for manufacturing immediately implanted tooth with periodontal bioactivity

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Embodiment Construction

[0012] The specific embodiments of the present invention will be described in detail below in conjunction with the accompanying drawings, and the content of the specific embodiments is not intended to limit the protection scope of the present invention.

[0013] The manufacturing method of the immediate implant with periodontal bioactivity according to the present invention utilizes the non-coating biological modification technology combining material science and tissue engineering technology to construct the artificial tooth root with bionic cementum structure, so that the prepared implant The tooth can be implanted immediately after tooth extraction, which has some life characteristics of natural implanted teeth, greatly shortens the restoration time of missing teeth, and significantly improves the success rate of implantation.

[0014] The idea of ​​the present invention is to use small molecule peptides to build biological activity, and use self-curing calcium phosphate mat...

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Abstract

The invention relates to a method for manufacturing an immediately implanted tooth with periodontal bioactivity. The method comprises the following steps: (1) preparing a pure titanium or titanium alloy implant core; (2) preparing self-curing calcium-magnesium phosphate powder; (3) preparing a collagen solution; (4) preparing an artificially synthesized P substance polypeptide; (5) preparing an SP crosslinking collagen substance; (6) mixing and stirring the calcium-magnesium phosphate powder and the SP crosslinking collagen substrate to prepare bioactive paste; (7) coating the root part of the implant core with the bioactive paste, pressurizing, curing and lyophilizing to prepare an artificial tooth root with periodontal bioactivity; (8) connecting the crown part of the implant core to an artificial tooth crown suitable for the tooth-missing appearance to obtain the immediately implanted tooth. According to the method, the artificial tooth root with a bionic cementum structure is constructed, so that the prepared implant tooth has partial life signs of a natural transplanted tooth, has spontaneous periodontal curing bioactivity, can be immediately implanted after a tooth is extracted, and can be used for remarkably shortening the tooth repairing time and improving the implant success rate.

Description

technical field [0001] The invention belongs to the technical field of dental artificial implants, and relates to a method for manufacturing biologically active dental implants, in particular to a method that can be implanted immediately after tooth extraction and actively induces the formation of osseointegration between the root of the implant and the bone tissue of the alveolar socket dental implant manufacturing method. Background technique [0002] Dental implant (dental implant) is called the third pair of teeth of human beings and has become a symbolic technology of modern stomatology. The development of modern dental implant technology is based on the theory of osseointegration (or osseointegration) proposed by Branemark, the father of implant in the 1960s. The American Academy of Dental Implantology defines osseointegration as: normal remodeled bone is in direct contact with the implant, soft tissue can be seen under a light-free microscope, and the load of the imp...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61C8/00A61L27/06A61L27/32A61L27/34A61L27/40A61L27/54
Inventor 周宏志王天珏胡开进丁宇翔侯锐胡文艳张林林
Owner FOURTH MILITARY MEDICAL UNIVERSITY
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