Chamber, soft tissue perfusion culture system and soft tissue tensile test system

Abstract

The invention discloses a cavity, a soft tissue perfusion culture system and a soft tissue stretchability test system. The cavity comprises an upper layer structure, a lower layer structure, two fixing blocks and two fixing parts. The soft tissue perfusion culture system comprises a liquid charge pump, a three-way valve, a liquid collecting device and the cavity. The soft tissue stretchability test system comprises a first fixture fixing plate, a second fixture fixing plate, a step motor, a base, a first fixing plate, a second fixing plate, an optical shaft, a linear sliding shaft and the soft tissue perfusion culture system. By utilizing the cavity, the soft tissue perfusion culture system and the soft tissue stretchability test system, the aseptic environment and perfusion culture conditions can be obtained when the soft tissue is stretched, and meanwhile, the stretching degree of the soft tissue can be controlled accurately.

Description

technical field [0001] The invention belongs to the field of mechanical automation and biotechnology, and relates to a chamber, a soft tissue perfusion culture system and a soft tissue tensile test system. Background technique [0002] Tissues in the body are in a complex growth environment, in which mechanical stimuli greatly affect the morphological structure and function of the tissue. Continuous passive tension promotes the lengthening and thickening of skeletal muscle tissue during human development, and physical labor and physical exercise can also increase the number and diameter of muscle fibers. Under physiological conditions, mechanical stress is an important extracellular stimulus to maintain cell survival and growth, affect cell growth behavior, regulate cell metabolism and gene expression process, and play an important role in cell activation, proliferation and differentiation. Studies have shown that mechanical stretching has a two-way effect on myoblasts. App...

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Problems solved by technology

[0003] Many foreign research groups have confirmed that periodic mechanical loading on the constructed muscle tissue, simulating the growth and development process of skeletal muscle tissue in vivo, can significantly affect the activity, life cycle and contractile function of the regenerated muscle tissue. However, in the soft tissue When stretching, it is difficult to obtain conditions such as sterile environment and perfusion culture. At the same time, when stretching soft tissues, the amount of stretching cannot be accurately controlled

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