Biosensing system for detecting biomarker concentration and detection method thereof

Abstract

The invention discloses a biosensing system for detecting biomarker concentration and a detection method thereof. The system comprises a light receiving module, an optoelectronic signal conversion module, a treatment module and an organic electroluminescent element, wherein the light receiving module is used for receiving an optical intensity signal emitted by the organic electroluminescent element and sending the optical intensity signal to the optoelectronic signal conversion module; the optoelectronic signal conversion module is used for amplifying the optical intensity signal, converting the optical intensity signal into an electric signal and converting the electric signal into a digital signal and outputting the digital signal to the treatment module; the treatment module is used for determining the concentration of a to-be-detected biomarker according to the change of the digital signal; the organic electroluminescent element comprises a light emitting body which comprises a light emitting layer made from an organic electroluminescent material. The invention further discloses a corresponding detection method. The light emitting characteristic of the organic electroluminescent material is applied to the field of biomacromolecular detection to detect the concentration of the to-be-detected biomarker, so that the application field of the organic electroluminescent material is expanded, the high-selectivity and high-specificity detection is realized, and moreover, the detection sensitivity of biomacromolecules is improved.

Description

technical field [0001] The invention relates to the technical field of biological detection, in particular to a biosensing system for detecting the concentration of biomarkers and a detection method thereof. Background technique [0002] Organic electroluminescent materials have been used in display, imaging and other fields due to their special luminescent properties. With the development of biotechnology, biomarkers such as proteins, DNA, antibodies, viruses, microorganisms, enzymes, and pesticides The detection method is constantly updated. Existing detection methods usually use detection instruments, but these detection instruments have disadvantages such as large volume, low detection sensitivity, high price, and narrow application fields. At present, how to convert biomolecules into fluctuating electrical signals that can be amplified in series, and how to achieve high-sensitivity, high-selectivity, high-specificity, and high-throughput composite detection are the key...

AI Technical Summary

Problems solved by technology

Existing detection methods usually use detection instruments, but these detection instruments have disadvantages such as large volume, low detection sensitivity, high price, and narrow application fields.

At present, how to convert biomolecules into fluctuating electrical signals that can be amplified in series, and how to achieve high-sensitivity, high-selectivity, high-specificity, and high-throughput composite detection are the keys to biomolecular detection. Therefore, it is necessary to have The luminescent properties of electroluminescent materials are applied to the detection of biological macromolecules to solve the shortcomings of existing detection methods such as high detection cost, low detection sensitivity, and narrow application fields.

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