Optical non-invasive detection method for oxygen saturation of mixed venous blood and oxygen saturation of central venous blood

A technology of central vein and detection method, applied in the field of medical devices, can solve the problems of inability to measure blood oxygen saturation relatively accurately, poor skin penetration, etc.

Inactive Publication Date: 2015-07-01
UNIV OF ELECTRONIC SCI & TECH OF CHINA
View PDF9 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this invention does not disclose or imply the specific algorithm of the measurement method of mixing and central venous blood oxygen saturation, and the light with a w

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Optical non-invasive detection method for oxygen saturation of mixed venous blood and oxygen saturation of central venous blood
  • Optical non-invasive detection method for oxygen saturation of mixed venous blood and oxygen saturation of central venous blood
  • Optical non-invasive detection method for oxygen saturation of mixed venous blood and oxygen saturation of central venous blood

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] In this embodiment the detector has two light sources and two wavelengths.

[0055] In step A, two light sources emitting near-infrared light of two wavelengths and a series of photosensitive detectors capable of detecting light attenuation changes of light transmitted back from the tissue to be measured constitute an optical detector, such as image 3 As shown, the typical values ​​of the two wavelengths here are λ 1 = 735nm and λ 2 = 850nm. In this example, the optical detector is placed on the neck of the subject for measurement. After the measurement is completed, the time is taken as the abscissa and the voltage is taken as the ordinate, and the output voltage measured by the optical detector is plotted as follows: Figure 4 , where the subscripts 1 and 2 represent light source 1 and light source 2, respectively. Through the function U(λ,t) of the measured output voltage signal changing with time t and the initial output voltage U 0 (λ) ratio, calculate the tra...

Embodiment 2

[0097] In this example, instead of taking Δ[HbO 2 ] and Δ[Hb] in the frequency domain, the signal generated by the frequency of about 1% of the respiratory frequency, but one of the other frequency bands is chosen arbitrarily. Calculated SvO 2 Most of them exceed the normal SvO of the human body 2 scope. Choose from a group of Figure 8 As shown, the four pictures on the left are Δ[HbO 2 ] r and Δ[Hb] r , the four graphs on the right are Δ[HbO 2 ] r and Δ[Hb] r , the difference is obvious. Therefore, the frequency band around 1% of the respiratory rate is the most suitable for measuring SvO 2 and ScvO 2 the frequency band.

Embodiment 3

[0099] In this embodiment, data verification is added in the calculation process, and its specific flow chart is as follows Figure 9 shown. The formula for calculating the signal-to-noise ratio is as follows:

[0100] SNR Hb = f { Δ [ Hb ] } f = r σ f = r

[0101] SNR HbO 2 = f { Δ [ Hb O 2 ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses an optical non-invasive detection method for oxygen saturation of mixed venous blood and oxygen saturation of central venous blood. Infrared light is adopted, an absorption spectrum of reflected light is measured, and specific mixed and central vein calculation methods are provided. Compared with existing testing methods for blood oxygen saturation, the optical non-invasive detection method not only achieves non-invasive detection but also can achieve real-time continuous monitoring. The specific algorithms are simple, effective and easy to achieve. During measurement, any part of a human body does not need to be clamped, only the body surface needs to be attached to, then the purpose can be achieved by measuring the absorption spectrum of the reflected light, a patient feels more comfortable during measurement, and measurement is simpler and more convenient. Besides, when the oxygen saturation of central venous blood is measured, jugular veins and subclavian veins are preferably selected for a target deep-layer vascular structure, and measurement is more accurate.

Description

technical field [0001] The invention belongs to the technical field of medical devices, in particular to a method for mixing and central venous blood oxygen saturation. Background technique [0002] Near Infrared Spectroscopy (NIRS for short) is a non-invasive, continuous and real-time optical diagnostic technology. , measure and calculate the light intensity attenuation of two or more wavelengths, and calculate the reduced hemoglobin (Hb) and oxygenated hemoglobin (HbO) through the absorption law 2 )content. [0003] From figure 1 See, in the near-infrared region, as the wavelength of light increases, Hb and HbO 2 The absorption coefficients show different trends, but Hb and HbO 2 There is an isoabsorptive point near the wavelength of 805nm. At present, the near-infrared light with two wavelengths of 760nm and 850nm is generally used as the medium to obtain blood oxygen information. [0004] Mixed venous oxygen saturation (SvO 2 ) refers to the blood oxygen saturatio...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61B5/1455
CPCA61B5/1455A61B5/0059
Inventor 李婷何田依依刘俊鹏潘伯安
Owner UNIV OF ELECTRONIC SCI & TECH OF CHINA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap