Spring coil and production method thereof

A spring coil, winding technology, applied in the field of medical equipment

Active Publication Date: 2015-07-01
MICROPORT NEUROTECH SHANGHAI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, issues such as the long-term safety of metals in the body and the mass effect of metal coils remain unresolved

Method used

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  • Spring coil and production method thereof
  • Spring coil and production method thereof
  • Spring coil and production method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] The spring wire chain is composed of platinum / tungsten alloy wire with good biocompatibility and degradable material polyglycolic acid / polylactic acid copolymer (PLGA). After PLGA is melted at high temperature, it is coated on the periphery of platinum / tungsten alloy wire by extrusion to form a spring wire chain. The diameter of the entire spring wire chain is 0.002″ (inch). The platinum / tungsten alloy wire accounts for 10% of the entire spring wire chain by volume, and the diameter is 0.0002″. A platinum / tungsten alloy wire makes the coil visible under X-rays. The first-stage spring of the spring ring is wound on a metal mandrel with a diameter of 0.003″ by a spring winding machine. The first-stage spring is as follows: figure 1 shown. Then the first-stage spring structure is wound around a 10mm stainless steel mandrel or a 10mm three-dimensional mold to form a basket, shaped and heat-treated, and implanted into the aneurysm by electrolysis. The embolization effect a...

Embodiment 2

[0032] The spring wire chain is composed of platinum / tungsten alloy wire with good biocompatibility and degradable material polyglycolic acid / polylactic acid copolymer (PLGA). After PLGA is melted at high temperature, it is coated on the periphery of platinum / tungsten alloy wire by extrusion to form a spring wire chain. The diameter of the entire spring wire chain is 0.0008″. The platinum / tungsten alloy wire accounts for 8% of the volume of the entire spring wire chain, and the diameter is 0.00008″. A platinum / tungsten alloy wire makes the coil visible under X-rays. The first-stage spring of the spring ring is wound on a metal mandrel with a diameter of 0.020 "with a spring winding machine. The first-stage spring is as follows: figure 1 shown. Then the first-stage spring structure is wound around a 1mm stainless steel mandrel or a 1mm three-dimensional mold to form a basket, heat-treated for shaping, the size is determined according to the size of the aneurysm, and the aneur...

Embodiment 3

[0034] The spring wire chain is composed of radiopaque iodide and the degradable material polyglycolic acid / polylactic acid copolymer (PLGA). After the PLGA particles are melted at high temperature, silk chains are formed by high temperature melt spinning. The silk chain is soaked in iodide (iodized oil) and dried to form a whole. The diameter of the whole spring wire chain is 0.0015 ". The volume ratio of iodide is 1%, which makes the coil visible under X-ray development. The first-stage spring of the coil is wound on a metal with a diameter of 0.007 " by a spring winding machine It is wound on the mandrel, and the primary spring is as figure 2 shown. Others are the same as the specification, heat treatment process and release method used in Example 1. With the degradation of biomaterials, the aneurysm will gradually shrink, and finally shrink to less than 1% of its original size, and even reach 0%. Figure 5 shown.

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Abstract

A spring coil and a preparation method thereof. The spring coil is formed by a winding wire strand. The wire strand comprises a degradable material and a radiopaque material that are processed to form an integral structure. A volume of the radiopaque material accounts for less than 10% of a volume of the wire strand. After the spring coil is implanted, biological materials induce a thrombus to form and organize. As the biological materials degrade, an aneurism gradually shrinks, and is finally reduced to less than 10% of an original size. The spring coil can accelerate healing, solving problems of long-term safety and space occupying effect of a bare metal spring coil in a body.

Description

technical field [0001] The invention relates to the field of medical instruments. Specifically, the present invention relates to a spring coil and its preparation method. Background technique [0002] Coil embolization is currently the main technique for the treatment of intracranial aneurysms. More than 85% of aneurysm patients are treated with this technique. Several coils are implanted into the aneurysm to cause thrombus in the cavity, and finally achieve the purpose of curing the aneurysm. [0003] Bare metal spring coils for embolization are mainly made of tungsten and platinum materials, and are shaped into different sizes and shapes in advance. However, problems such as low filling rate and recurrence of aneurysm often occur. [0004] Therefore, hydrogel coils and biomodified coils have been proposed, hoping to reduce the recanalization rate of aneurysms. Due to its unique biocompatibility and therapeutic effect, it is the future development direction of coil prod...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B17/12
CPCA61B17/12A61B17/12113A61B17/1214A61B17/12145A61B17/1215A61B17/1219A61B2017/00942
Inventor 郭远益贾国庆陈冰张玉成金巧蓉刘玉梅谢志永
Owner MICROPORT NEUROTECH SHANGHAI
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