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Medicament for treating active ulcerative colitis

An ulcerative colitis and drug technology, applied in the field of traditional Chinese medicine, can solve the problems of poor patient compliance and large side effects of treatment, and achieve the effects of good patient compliance, quick effect, and no side effects.

Inactive Publication Date: 2015-07-29
QINGDAO HUAREN TECH INCUBATOR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the western medicines commonly used in the treatment of ulcerative colitis mainly include 5-aminosalicylic acid drugs, corticosteroids, immunosuppressants and antibiotics, etc., but the side effects of treatment are relatively large, and patients’ compliance is poor.

Method used

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  • Medicament for treating active ulcerative colitis
  • Medicament for treating active ulcerative colitis

Examples

Experimental program
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Effect test

preparation example Construction

[0051] The present invention also provides the preparation method of above-mentioned medicine, it comprises:

[0052] The first step is to take oxtail ginseng, scallion white, golden cherry, puhuang, selaginella, white scorpion, kudzu root, dendrobium, gorgon, psoralen and jujube, respectively, ultrafinely pulverize, mix, extract with ethanol, then purify and pulverize into the first powder;

[0053] In the second step, the remaining components are superfinely pulverized, mixed, extracted with water, dried, and pulverized into a second powder;

[0054] In the third step, the first powder and the second powder are mixed, and various oral preparations are prepared by adding pharmaceutically acceptable auxiliary materials according to different dosage forms.

[0055] The first step is further specifically to take oxtail ginseng, scallion white, rosa chinensis, puhuang, selaginella, white scorpion, kudzu root, dendrobium, gorgon, psoralen and jujube and place them in an ultrafine...

Embodiment 1

[0060] Embodiment 1 Granule 1

[0061] Take 35g of oxtail ginseng, 20g of scallion white, 15g of golden cherry, 20g of Puhuang, 15g of Selaginella, 20g of white scorpion, 20g of kudzu root, 15g of Dendrobium, 20g of gorgon, 15g of psoraleae and 15g of jujube and place them in the ultrafine pulverizer respectively Pulverize for 40 minutes, mix the pulverized powders to obtain a mixture, dissolve in 850 g of ethanol with an alcohol concentration of 80%, extract 3 times under reflux, filter, combine the filtrates, concentrate under reduced pressure to remove ethanol, obtain a dry paste, and then dry , pulverized for 40 minutes with an ultrafine pulverizer, the powder after pulverization was dissolved in 850 g of water, filtered, added with a concentration of 10% hydrochloric acid to adjust the pH value to 3, left to stand for 4 hours, filtered, the filtrate was extracted with ethanol, and the extract was reduced Press and condense into a dry paste, then dry, crush into 100-mesh f...

Embodiment 2

[0062] Embodiment 2 Granules 2

[0063] Take 32g of oxtail ginseng, 17g of scallion white, 12g of golden cherry, 17g of Puhuang, 12g of selaginella, 17g of white scorpion, 17g of kudzu root, 12g of dendrobium, 17g of gorgon, 12g of psoralen and 12g of jujube and place them in the ultrafine pulverizer respectively Grinding for 40 minutes, mixing the pulverized powders to obtain a mixture, dissolving in 800 g of ethanol with an alcohol concentration of 80%, refluxing and extracting 3 times, filtering, combining the filtrates, concentrating under reduced pressure to remove ethanol, obtaining a dry paste, and then drying , pulverized for 40 minutes with an ultrafine pulverizer, the powder after pulverization was dissolved in 850 g of water, filtered, added with a concentration of 10% hydrochloric acid to adjust the pH value to 3, left to stand for 4 hours, filtered, the filtrate was extracted with ethanol, and the extract was reduced Press and condense into a dry paste, then dry, ...

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Abstract

The invention provides a medicament for treating the active ulcerative colitis, which comprises the raw material medicines: dioscorea hemsleyi, allium macrostemon, scrophularia ningpoensis, geranium wilfordii, rosa laevigata, houttuynia cordata, cattail pollen, selaginella, ampelopsis japonica, coix seeds, kudzuvine root, coptis chinensis, dendrobium nobile, capitate knotweed herb, gorgon euryale seed, fructus psoraleae and Chinese dates. Compared with Western medicine such as antibiotics and the like, the medicament has a good curative effect and a high response speed, has no toxic or side effects and has good patient compliance.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a medicine for treating active ulcerative colitis. Background technique [0002] Ulcerative colitis is a chronic non-specific inflammatory disease of the colon. The clinical manifestations are persistent or recurrent diarrhea, mucus, pus and blood in the stool, accompanied by abdominal pain and tenesmus as the main symptoms of common gastroenterological diseases. [0003] With the changes in people's living habits and dietary structure, the increase in the rate of medical visits, the deepening of the understanding of the disease and the improvement of diagnostic methods, the incidence of ulcerative colitis is increasing day by day. The number of reports has increased dramatically, and there is an increasing trend. Ulcerative colitis lesions mainly affect the intestinal mucosa, mainly the colon, mostly involving the distal colon, and can extend to the proxima...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61P1/00A61P1/04
Inventor 孙霞
Owner QINGDAO HUAREN TECH INCUBATOR
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