Nanoparticle formulation
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- 英国研究与创新署
- Publication Date
- 2015-08-12
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Abstract
Description
technical field
[0001] The present invention relates to nanoparticle formulations. In particular, it relates to, but is not limited to, nanoparticle-assisted delivery of therapeutic agents for the treatment of metabolism and cancer. Background technique
[0002] Dysregulation of cellular metabolism is a central prerequisite for many chronic disease processes, including cancer. Recently, there has been renewed interest in the potential of metabolic engineering to retransform abnormal cells and tissues through the use of small molecules. However, achieving sufficient and sustained metabolic effects by such methods can be difficult due to the need to identify suitable small molecules and develop suitable modes of administration.
[0003] Metabolic engineering provides a powerful and efficient tool as it allows the systematic manipulation and fine-tuning of cellular metabolic activity. Methods to reengineer metabolism in dysregulated or oncogenic states are needed. The metho...